Specyficzna rekrutacja regulatorowych limfocytów T w raku jajnika

Societatea Romana de Stiinte Fiziologice  > ELISA kit, immune, Immunoblotting, miRNA >  Specyficzna rekrutacja regulatorowych limfocytów T w raku jajnika
srsf

Specyficzna rekrutacja regulatorowych limfocytów T w raku jajnika

0 Comments

Płynny mannequin mozaiki struktury błon komórkowych.

 Este prezentat un mannequin de mozaic fluid pentru organizarea și structura brută a proteinelor și lipidelor membranelor biologice. Modelul este în concordanță cu restricțiile impuse de termodinamică. În acest mannequin, proteinele care fac parte integrantă din membrană sunt un set eterogen de molecule globulare, fiecare dispuse într-o structură amfipatică, adică cu grupările ionice și extrem de polare care ies din membrană în faza apoasă și grupurile nepolare. în mare măsură îngropat în interiorul hidrofob al membranei. Aceste molecule globulare sunt parțial încorporate într-o matrice de fosfolipide. Cea mai mare parte a fosfolipidelor este organizată ca un strat strat discontinuu, fluid, deși o mică parte a lipidei poate interacționa în mod particular cu proteinele de membrană.

Structura mozaicului fluid este, prin urmare, în mod formal similară cu o soluție bidimensională orientată de proteine ​​integrale (sau lipoproteine) în solventul bistrat cu fosfolipide vâscoase. Sunt descrise experimente recente cu o mare varietate de tehnici și mai multe sisteme de membrană diferite, toate acestea fiind compatibile cu modelul mozaicului fluid și îi adaugă multe detalii. Prin urmare, pare adecvat să sugerăm posibile mecanisme pentru diferite funcții ale membranei și fenomene mediate de membrană în lumina modelului. Ca exemple, sunt sugerate mecanisme testabile experimental pentru   modificările suprafeței celulare în transformarea malignă și pentru efectele de cooperare prezentate în interacțiunile membranelor cu unii liganzi specifici.

Notă adăugată în dovadă: De când a fost scris acest articol, am obținut dovezi microscopice electronice (69) conform cărora situsurile de legare a concanavalinei A pe membranele fibroblastelor de șoarece transformate de virusul SV40 ( celule 3T3  ) sunt mai grupate decât siturile de pe membranele celule normale  , după cum se prezice prin ipoteza reprezentată în Fig. 7B. A apărut și un studiu realizat de Taylor și colab. (70) care arată efectele remarcabile produse asupra  limfocitelor  prin adăugarea de anticorpi direcționați către moleculele lor de imunoglobulină de suprafață.

Anticorpii induc o redistribuire și pinocitoză a acestor imunoglobuline de suprafață, astfel încât în ​​aproximativ 30 de minute la 37 de grade C imunoglobulinele de suprafață sunt complet măturate din membrană. Aceste efecte nu apar, totuși, dacă anticorpii bivalenți sunt înlocuiți cu fragmentele lor Fab univalente sau dacă experimentele de anticorpi sunt efectuate la zero grade C în loc de 37 grade C.

Aceste și rezultatele conexe indică cu tărie că anticorpii bivalenți produc o agregare a moleculelor de imunoglobulină de suprafață în planul membranei, care pot apărea numai dacă moleculele de imunoglobulină sunt libere să difuzeze în membrană . Această agregare atuncipare să declanșeze pinocitoza componentelor membranei printr-un mecanism necunoscut. Astfel de transformări de membrană pot avea o importanță crucială în inducerea unui răspuns de anticorp la un antigen, precum și iv alte procese de   diferențiere celulară .

srsf
srsf

mAdrb2 CRISPR Knock Out B16 Cell Line (T1-10)

T9775 1x10^6 cells / 1.0 ml Ask for price

MUC16 CRISPR Knock Out Human OVCAR3-A1 Cell Line

T6230 1x10^6 cells / 1.0 ml Ask for price

Ccl2 CRISPR Knock Out CT26 Cell Line

T9611 1x10^6 cells / 1.0 ml Ask for price

CXCL8 CRISPR Knock Out L3.6pl Cell Line

T6220 1x10^6 cells / 1.0 ml Ask for price

CXCL1 CRISPR Knock Out L3.6pl Cell Line

T6221 1x10^6 cells / 1.0 ml Ask for price

NR2F6 CRISPR Knock Out Human Jurkat E6.1 Cell Line - Clone T3-10

T6822 1x10^6 cells / 1.0 ml Ask for price

TREM2 CRISPR Knock Out Human THP-1 Cell Line - Clone T1-9

T6810 1x10^6 cells / 1.0 ml Ask for price

PTPN6 CRISPR Knock Out Human THP-1 Cell Line - Clone T3-1

T6813 1x10^6 cells / 1.0 ml Ask for price

Aldh2 CRISPR Knock Out L929 Cell Line - Clone T3-20

T9692 1x10^6 cells / 1.0 ml Ask for price

PTPN11 CRISPR Knock Out NIH/3T3 Cell Line - Clone T4-9

T6803 1x10^6 cells / 1.0 ml Ask for price

PRSS21 CRISPR Knock Out Human OVCAR8 Cell Line - Clone T2 C8

T6811 1x10^6 cells / 1.0 ml Ask for price

METTL3 CRISPR Knock Out Caki-1 Cell Line - Clone T2-16

T9623 1x10^6 cells / 1.0 ml
EUR 3950

Nacc1 CRISPR Knock Out ID8 Cell Line (Mouse) - Clone T1-23

T9627 1x10^6 cells / 1.0 ml Ask for price

osbpl2 CRISPR Knock Out NIH/3T3 Cell Line - T1 Polyclonal Pool

T9682 1x10^6 cells / 1.0 ml Ask for price

GLT1 CRISPR Knock Out Rat AST Cell Line - Clone T2-1

T9678 1x10^6 cells / 1.0 ml Ask for price

Aifm1 CRISPR Knock Out Mouse L929 Cell Line - Clone T2-15-3

T9674 1x10^6 cells / 1.0 ml Ask for price

SEC61G CRISPR Knock Out HCC-LM3 Cell Line - Clone T2-17-5

T9746 1x10^6 cells / 1.0 ml Ask for price

MSLN CRISPR Knock Out Human OVCAR3-A1 Cell Line - Clone T2 C4

T6820 1x10^6 cells / 1.0 ml Ask for price

CARMIL1 CRISPR Knock Out Immortalized Human Gingival Fibroblast - hTERT Cell Line - T1-2

T6825 1x10^6 cells / 1.0 ml Ask for price

hPIM1 CRISPR Knock Out SACC-83 Cell Line-T3-9

T9787 1x10^6 cells / 1.0 ml Ask for price

Dcx CRISPR Knock Out C6 Cell Line (Rat) - Clone sg4-1

T9624 1x10^6 cells / 1.0 ml
EUR 3950

Cell line gene knock-in and knock-out

S301 -
EUR 15000

Araf CRISPR Knocked out RAW264.7 Stable cell Cell Line (Mouse) T1-19

T9511 1x10^6 cells / 1.0 ml
EUR 3950

Araf CRISPR Knocked out RAW264.7 Stable cell Cell Line (Mouse) T3-3

T9529 1x10^6 cells/1.0ml
EUR 3950

SIRT1 Knockout Stable 293T Cell Line

T3176 1x10^6 cells / 1.0 ml
EUR 3950

Human LCK knockout cell line

ABC-KH8337 1 vial Ask for price
Description: Human LCK knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human LCK knockdown cell line

ABC-KD8337 1 vial Ask for price
Description: Human LCK knockdown cell line is engineered by our optimized transduction of the specific shRNA with lentivirus. Knockdown levels are determined via qRT-PCR. Gentaur offers generation of stable knockdown (RNAi) cell lines expressing shRNAs targeting genes of your interest.

T47D/GFP Cell Line

AKR-208 1 vial
EUR 686.4
Description: T47D/GFP Cell Line stably expresses GFP and otherwise exhibits the same characteristics of the parental cell line.

Stable Mouse Myeloid-derived Suppressor-like LAL Knock Out (HD1B) Cell Line

T3187 1x10^6 cells / 1.0 ml
EUR 3950

293T Cell Line

LV010 1x10^6
EUR 450

293T [HEK-293T] Cell Line

CL-0005 1×10⁶ cells/vial
EUR 420
Description: Homo sapiens, Human

Mouse NACC1 CRISPR Stable Knockout ID8 Cell Line - Clone T1-23

T6826 1x10^6 cells / 1.0 ml
EUR 3950

293T/17 Cell Line

CL-0469 1×10⁶ cells/vial
EUR 500
Description: Homo sapiens, Human

293T Cell Lysate (Human embryonic kidney cell line)

LF-R0006 200 ul
EUR 103.2
Description: 293T (Human embryonic kidney cell line) Whole Cell Lysate

BRCA1 CRISPR Stable Knockout Human Fibroblast Cell Line

T6245 1x10^6 cells / 1.0 ml
EUR 3950

Blank Promoter Stable Expressing Human 293T Cell Line

T9618 1x10^6 cells / 1.0 ml
EUR 3950

PTPRA CRISPR Knockout Immortalized Human Lung Fibroblast Cell Line

T6827 1x10^6 cells / 1.0 ml Ask for price

293AD Cell Line

AD-100 1 vial
EUR 365

293AAV Cell Line

AAV-100 1 vial
EUR 405

293LTV Cell Line

LTV-100 1 vial
EUR 405

293RTV Cell Line

RV-100 1 vial
EUR 405

Cas9 Expressing 293T Cell Line

T3251 1x10^6 cells / 1.0 ml
EUR 795

293/GFP Cell Line

AKR-200 1 vial
EUR 460

Human CRISP1 knockout cell line

ABC-KH3569 1 vial Ask for price
Description: Human CRISP1 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human CRISP2 knockout cell line

ABC-KH3570 1 vial Ask for price
Description: Human CRISP2 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human CRISP3 knockout cell line

ABC-KH3571 1 vial Ask for price
Description: Human CRISP3 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

A549/GFP Cell Line

AKR-209 1 vial
EUR 460

HeLa/GFP Cell Line

AKR-213 1 vial
EUR 460

293/Cas9 Cell Line

AKR-5110 1 vial
EUR 460

HeLa/Cas9 Cell Line

AKR-5111 1 vial
EUR 460

NIH3T3/GFP Cell Line

AKR-214 1 vial
EUR 460

Stable 293T-ATD cell line

T6340 1x10^6 cells / 1.0 ml
EUR 3950

NIH3T3/Cas9 Cell Line

AKR-5104 1 vial
EUR 460

Acan CRISPR Knockout RCS Cell Line (Rat)

T3000 1x10^6 cells / 1.0 ml Ask for price

PTPN6 Stable Knocked Out THP-1 Cell Line

T6216 1x10^6 cells / 1.0 ml
EUR 3950

Human CRISPLD1 knockout cell line

ABC-KH3572 1 vial Ask for price
Description: Human CRISPLD1 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human CRISPLD2 knockout cell line

ABC-KH3573 1 vial Ask for price
Description: Human CRISPLD2 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

MCF-7/Luc Cell Line

AKR-234 1 vial
EUR 686.4
Description: MCF-7/Luc Cell Line stably expresses luciferase and otherwise exhibits the same characteristics of the parental cell line.

SKOV-3/Luc Cell Line

AKR-232 1 vial
EUR 686.4
Description: SKOV-3/Luc Cell Line stably expresses luciferase and otherwise exhibits the same characteristics of the parental cell line.

OVCAR-5/RFP Cell Line

AKR-254 1 vial
EUR 686.4
Description: OVCAR-5/RFP Cell Line stably expresses RFP and otherwise exhibits the same characteristics of the parental cell line.

Human CRISP1 knockdown cell line

ABC-KD3569 1 vial Ask for price
Description: Human CRISP1 knockdown cell line is engineered by our optimized transduction of the specific shRNA with lentivirus. Knockdown levels are determined via qRT-PCR. Gentaur offers generation of stable knockdown (RNAi) cell lines expressing shRNAs targeting genes of your interest.

Human CRISP2 knockdown cell line

ABC-KD3570 1 vial Ask for price
Description: Human CRISP2 knockdown cell line is engineered by our optimized transduction of the specific shRNA with lentivirus. Knockdown levels are determined via qRT-PCR. Gentaur offers generation of stable knockdown (RNAi) cell lines expressing shRNAs targeting genes of your interest.

Human CRISP3 knockdown cell line

ABC-KD3571 1 vial Ask for price
Description: Human CRISP3 knockdown cell line is engineered by our optimized transduction of the specific shRNA with lentivirus. Knockdown levels are determined via qRT-PCR. Gentaur offers generation of stable knockdown (RNAi) cell lines expressing shRNAs targeting genes of your interest.

SIRT1 Wildtype Stable 293T Cell Line

T3175 1x10^6 cells / 1.0 ml
EUR 3950

TARGATT? Knock-in Mouse Cell Line Generation Kit (Master Cell Line)

AST-7001 1 Kit Ask for price
Description: 6 month

Human CRISPLD1 knockdown cell line

ABC-KD3572 1 vial Ask for price
Description: Human CRISPLD1 knockdown cell line is engineered by our optimized transduction of the specific shRNA with lentivirus. Knockdown levels are determined via qRT-PCR. Gentaur offers generation of stable knockdown (RNAi) cell lines expressing shRNAs targeting genes of your interest.

Human CRISPLD2 knockdown cell line

ABC-KD3573 1 vial Ask for price
Description: Human CRISPLD2 knockdown cell line is engineered by our optimized transduction of the specific shRNA with lentivirus. Knockdown levels are determined via qRT-PCR. Gentaur offers generation of stable knockdown (RNAi) cell lines expressing shRNAs targeting genes of your interest.

GFAT1 CRISPR Stable Knockout H1299 Cell Line

T6199 1x10^6 cells / 1.0 ml
EUR 3950

EDC4 CRISPR Stable Knockout HEK293T Cell Line

T6241 1x10^6 cells / 1.0 ml
EUR 3950

DJ-1 CRISPR Stable Knockout HeLa Cell Line

T6181 1x10^6 cells / 1.0 ml
EUR 3950

PGC-1α/ERRα Stable 293T Cell Line

T3060 1x10^6 cells / 1.0 ml
EUR 385

YBX1 Stable Knockout Human NK/T Cell Line #T3-16 P6

T9508 1x10^6 cells / 1.0 ml Ask for price

PDPN CRISPR Stable Knockout COS-7 Cell Line

T6039 1x10^6 cells / 1.0 ml
EUR 3950

PD-L1 CRISPR Stable Knockout CT26 Cell Line

T6237 1x10^6 cells / 1.0 ml
EUR 3950

PD-L1 CRISPR Stable Knockout MC38 Cell Line

T6149 1x10^6 cells / 1.0 ml
EUR 3950

LIMD1-/- CRISPR Stable Knockout HeLa Cell Line

T6357 1x10^6 cells / 1.0 ml
EUR 3950

Mouse R-spondin1 Stable 293T Cell Line

T3156 1x10^6 cells / 1.0 ml
EUR 3950

TARGATT? Knock-in iPSC Generation (Master Cell Line)

AST-1100 1 vial of 1X10^6 cells Ask for price
Description: 6 month

SLC35A1 CRISPR Stable Knockout CHO-S Cell Line

T6040 1x10^6 cells / 1.0 ml
EUR 3950

CXCL1 & CXCL8 CRISPR Double Knockout L3.6pl Cell Line

T6047 1x10^6 cells / 1.0 ml Ask for price

Platinum-E Retroviral Packaging Cell Line, Ecotropic

RV-101 1 vial
EUR 770

Platinum-GP Retroviral Packaging Cell Line, Pantropic

RV-103 1 vial
EUR 770

Platinum-A Retroviral Packaging Cell Line, Amphotropic

RV-102 1 vial
EUR 770

PFN2 Stable Expressing 293T Cell Line - Polyclonal

T9606 1x10^6 cells / 1.0 ml
EUR 3950

Total Protein - Murine Embryonic Stem Cell Line D3

CBA-305 500 ?g
EUR 414
Description:
  • Isolated from mouse ES-D3 cell line
  • Presented as 500 µg at 1 mg/mL in NP-40 Solubilization Buffer

PLN Knock-out Human Induced Pluripotent Stem Cells (Episomal, HFF)

iPS41 1 Vial
EUR 2268

AXL CRISPR Stable Knockout HT1080 (1-IV) Cell Line

T6232 1x10^6 cells / 1.0 ml
EUR 3950

AXL CRISPR Stable Knockout HT1080 (3-II) Cell Line

T6233 1x10^6 cells / 1.0 ml
EUR 3950

LRP1 Knock-out Human Induced Pluripotent Stem Cells (Episomal, HFF)

iPS31 1 Vial
EUR 2268

AFF2 Knock-out Human Induced Pluripotent Stem Cells (Episomal, HFF)

iPS61 1 Vial
EUR 2268

ABCA7 Knock-out Human Induced Pluripotent Stem Cells (Episomal, HFF)

iPS21 1 Vial
EUR 2268

KCNK3 Knock-out Human Induced Pluripotent Stem Cells (Episomal, HFF)

iPS51 1 Vial
EUR 2268

LLGL1 Knock-out Human Induced Pluripotent Stem Cells (Episomal, HFF)

iPS71 1 Vial
EUR 2268

TARGATT? Knock-in CHO Generation Kit (Master Cell Line)

AST-1200 1 Kit Ask for price
Description: 12 month

TARGATT? Knock-in HEK293 Generation Kit (Master Cell Line)

AST-1300 1 Kit Ask for price
Description: 12 month

Human CRIM1 knockout cell line

ABC-KH3563 1 vial Ask for price
Description: Human CRIM1 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human CRIP1 knockout cell line

ABC-KH3564 1 vial Ask for price
Description: Human CRIP1 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human CRIP2 knockout cell line

ABC-KH3565 1 vial Ask for price
Description: Human CRIP2 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human CRIP3 knockout cell line

ABC-KH3566 1 vial Ask for price
Description: Human CRIP3 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human CRIPT knockout cell line

ABC-KH3568 1 vial Ask for price
Description: Human CRIPT knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human CRIPAK knockout cell line

ABC-KH3567 1 vial Ask for price
Description: Human CRIPAK knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human 293T Cell Lysate Lyophilized

IHU293TTLLY200UG each
EUR 89
Description: Human 293T Cell Lysate Lyophilized

Human 293T Cell Lysate Lyophilized

MBS136608-02mg 0.2mg
EUR 205

Human 293T Cell Lysate Lyophilized

MBS136608-5x02mg 5x0.2mg
EUR 745

AAVS1 Positive Control EGIP 293T Reporter Cell Line

CAS606A-1 1 Vial
EUR 726

VEGF Promoter Stable Expressing 293T Cell Line - Clone #2

T9622 1x10^6 cells / 1.0 ml
EUR 3950

Human 293T Whole Cell Lysate

LYSATE0032 200ug
EUR 180
Description: This cell lysate is prepared from human 293T using Boster's RIPA Lysis Buffer (AR0105) using a standard whole cell lysate protocol. The concentration was determined using the BCA assay process and then diluted using Dithiothreitol (DTT) and a reducing SDS sample loading buffer, heated for 5 minutes at 100˚C.

Human CRIM1 knockdown cell line

ABC-KD3563 1 vial Ask for price
Description: Human CRIM1 knockdown cell line is engineered by our optimized transduction of the specific shRNA with lentivirus. Knockdown levels are determined via qRT-PCR. Gentaur offers generation of stable knockdown (RNAi) cell lines expressing shRNAs targeting genes of your interest.

Human CRIP1 knockdown cell line

ABC-KD3564 1 vial Ask for price
Description: Human CRIP1 knockdown cell line is engineered by our optimized transduction of the specific shRNA with lentivirus. Knockdown levels are determined via qRT-PCR. Gentaur offers generation of stable knockdown (RNAi) cell lines expressing shRNAs targeting genes of your interest.

Human CRIP2 knockdown cell line

ABC-KD3565 1 vial Ask for price
Description: Human CRIP2 knockdown cell line is engineered by our optimized transduction of the specific shRNA with lentivirus. Knockdown levels are determined via qRT-PCR. Gentaur offers generation of stable knockdown (RNAi) cell lines expressing shRNAs targeting genes of your interest.

Human CRIP3 knockdown cell line

ABC-KD3566 1 vial Ask for price
Description: Human CRIP3 knockdown cell line is engineered by our optimized transduction of the specific shRNA with lentivirus. Knockdown levels are determined via qRT-PCR. Gentaur offers generation of stable knockdown (RNAi) cell lines expressing shRNAs targeting genes of your interest.

Human CRIPT knockdown cell line

ABC-KD3568 1 vial Ask for price
Description: Human CRIPT knockdown cell line is engineered by our optimized transduction of the specific shRNA with lentivirus. Knockdown levels are determined via qRT-PCR. Gentaur offers generation of stable knockdown (RNAi) cell lines expressing shRNAs targeting genes of your interest.

hCETP shRNA (Target C) Knock Down THP-1 Cell Line-Polyclone

T9789 1x10^6 cells / 1.0 ml Ask for price

Human CRIPAK knockdown cell line

ABC-KD3567 1 vial Ask for price
Description: Human CRIPAK knockdown cell line is engineered by our optimized transduction of the specific shRNA with lentivirus. Knockdown levels are determined via qRT-PCR. Gentaur offers generation of stable knockdown (RNAi) cell lines expressing shRNAs targeting genes of your interest.

Human LIN37 knockout cell line

ABC-KH8476 1 vial Ask for price
Description: Human LIN37 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human GC knockout cell line

ABC-KH5948 1 vial Ask for price
Description: Human GC knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human GK knockout cell line

ABC-KH6087 1 vial Ask for price
Description: Human GK knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human HP knockout cell line

ABC-KH6972 1 vial Ask for price
Description: Human HP knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human HR knockout cell line

ABC-KH6992 1 vial Ask for price
Description: Human HR knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human KL knockout cell line

ABC-KH7942 1 vial Ask for price
Description: Human KL knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Sierocy receptor jądrowy RORgammat kieruje programem różnicowania prozapalnych komórek pomocniczych IL-17 + T.

IL-17-T producătoare  de limfocite  au fost current dovedit a cuprinde o descendență distinctă de T helper proinflamatorii  celule , numite Th17  celule , care sunt o contributie majora la boli autoimune. Arătăm aici că receptorul nuclear orfan RORgammat este factorul cheie de transcripție care orchestrează diferențierea acestei  linii de celule efectoare  . RORgammat induce transcripția genelor care codifică IL-17 și IL-citokina înrudit 17F în naivi CD4 (+) T helper  celule  și este necesar pentru exprimarea lor ca răspuns la IL-6 și TGF-beta, citokinele cunoscute de a induce IL- 17.

Celulele Th17   sunt prezente în mod constitutiv în toată lamina propria intestinală, exprimă RORgammat și sunt absente la șoareci cu deficit de RORgammat sau IL-6. Șoarecii cu celule T cu deficit de RORgammat   au boli autoimune atenuate și nu au celule Th17 care se infiltrează în țesuturi  . Împreună, aceste studii sugerează că RORgammat este un regulator cheie al homeostaziei imune și evidențiază potențialul său ca țintă terapeutică în bolile inflamatorii.

Specyficzna rekrutacja regulatorowych limfocytów T w raku jajnika sprzyja przywilejowi immunologicznemu i pozwala przewidzieć skrócenie czasu przeżycia.

 

T de reglementare (T (REG))  Celulele  mediază toleranță periferică homeostatic prin suprimarea T autoreactive  celule . Nerespectarea imunității antitumorale gazdă poate fi cauzată de supresia exagerată antigen reactive asociate tumorii  limfocite  mediate de T (REG)  celule ; Cu toate acestea, dovezi definitive care (REG) T  celule  au un rol imunopatologice in cancerul uman este lipsit. Aici ne arată, în studii detaliate ale CD4 (+) CD25 (+) FOXP3 (+) T (REG)  celule  in 104 persoane afectate cu carcinom ovarian, tumoarea umană T (REG)  celule  suprima T-tumorale specifice  celulei  imunitate și contribuie la creșterea tumorilor umane in vivo.

De asemenea, arătăm că celulele T (reg)  tumorale  sunt asociate cu un risc crescut de deces și supraviețuire redusă. Celulele T (reg)  umane  se deplasează și se acumulează preferențial în tumori și ascită, dar rareori intră în ganglionii limfatici care drenează în stadiile ulterioare ale cancerului.

Celulele tumorale   și macrofagele microambientale produc chemokina CCL22, care mediază traficul de celule T (reg)   către tumoră. Această recrutare specifică a celulelor T (reg)   reprezintă un mecanism prin care tumorile pot favoriza privilegiul imunitar. Astfel, blocarea  migrației sau funcției celulelor T (reg)  poate ajuta la înfrângerea cancerului uman.

Przywracanie funkcji wyczerpanych limfocytów T CD8 podczas przewlekłej infekcji wirusowej

Afectarea funcțională a celulelor T specifice antigenului   este o caracteristică definitorie a multor infecții cronice, dar mecanismele de bază ale  disfuncției celulelor T nu sunt bine înțelese. Pentru a rezolva această problemă, am analizat genele exprimate in afectarea useful virus-specific T CD8  celule  prezente la șoarecii infectați cronic cu virusul coriomeningitei limfocitare (LCMV) și a comparat aceste cu profilul genetic al T CD8 memorie functionale  celule .

Aici raportăm că PD-1 (moartea programată 1; cunoscut și sub numele de Pdcd1) a fost selectiv reglat în sus de celulele T epuizate și că administrarea in vivo a anticorpilor care a blocat interacțiunea acestui receptor inhibitor cu ligandul său, PD-L1 (cunoscut și ca B7-H1), a îmbunătățit  răspunsurile celulelor T.

In particular, am constatat ca , chiar si la soareci persistent infectate care au fost lipsite de celule CD4 T de celule de  ajutor, blocarea PD-1 / PD-L1 cale de inhibare a avut un efect benefic asupra „neajutorat“ T CD8  celule , restabilind capacitatea lor de a suferi proliferare , secretă citokine, ucid celulele infectate   și scad încărcătura virală. Blocarea căii inhibitoare a CTLA-4 ( proteina Four asociată cu limfocitele T citotoxice ) nu a avut niciun efect nici asupra  funcției celulelor T , nici asupra controlului viral. Aceste studii identifică un mecanism particular de  epuizare a celulelor T și definesc o strategie imunologică potențial eficientă pentru tratamentul infecțiilor virale cronice.

Ccl2 CRISPR Knock Out CT26 Cell Line

T9611 1x10^6 cells / 1.0 ml Ask for price

CXCL8 CRISPR Knock Out L3.6pl Cell Line

T6220 1x10^6 cells / 1.0 ml Ask for price

CXCL1 CRISPR Knock Out L3.6pl Cell Line

T6221 1x10^6 cells / 1.0 ml Ask for price

NR2F6 CRISPR Knock Out Human Jurkat E6.1 Cell Line - Clone T3-10

T6822 1x10^6 cells / 1.0 ml Ask for price

TREM2 CRISPR Knock Out Human THP-1 Cell Line - Clone T1-9

T6810 1x10^6 cells / 1.0 ml Ask for price

PTPN6 CRISPR Knock Out Human THP-1 Cell Line - Clone T3-1

T6813 1x10^6 cells / 1.0 ml Ask for price

Aldh2 CRISPR Knock Out L929 Cell Line - Clone T3-20

T9692 1x10^6 cells / 1.0 ml Ask for price

PTPN11 CRISPR Knock Out NIH/3T3 Cell Line - Clone T4-9

T6803 1x10^6 cells / 1.0 ml Ask for price

PRSS21 CRISPR Knock Out Human OVCAR8 Cell Line - Clone T2 C8

T6811 1x10^6 cells / 1.0 ml Ask for price

METTL3 CRISPR Knock Out Caki-1 Cell Line - Clone T2-16

T9623 1x10^6 cells / 1.0 ml
EUR 3950

Nacc1 CRISPR Knock Out ID8 Cell Line (Mouse) - Clone T1-23

T9627 1x10^6 cells / 1.0 ml Ask for price

osbpl2 CRISPR Knock Out NIH/3T3 Cell Line - T1 Polyclonal Pool

T9682 1x10^6 cells / 1.0 ml Ask for price

GLT1 CRISPR Knock Out Rat AST Cell Line - Clone T2-1

T9678 1x10^6 cells / 1.0 ml Ask for price

Aifm1 CRISPR Knock Out Mouse L929 Cell Line - Clone T2-15-3

T9674 1x10^6 cells / 1.0 ml Ask for price

SEC61G CRISPR Knock Out HCC-LM3 Cell Line - Clone T2-17-5

T9746 1x10^6 cells / 1.0 ml Ask for price

MSLN CRISPR Knock Out Human OVCAR3-A1 Cell Line - Clone T2 C4

T6820 1x10^6 cells / 1.0 ml Ask for price

CARMIL1 CRISPR Knock Out Immortalized Human Gingival Fibroblast - hTERT Cell Line - T1-2

T6825 1x10^6 cells / 1.0 ml Ask for price

hPIM1 CRISPR Knock Out SACC-83 Cell Line-T3-9

T9787 1x10^6 cells / 1.0 ml Ask for price

Dcx CRISPR Knock Out C6 Cell Line (Rat) - Clone sg4-1

T9624 1x10^6 cells / 1.0 ml
EUR 3950

Human GZMA knockout cell line

ABC-KH6566 1 vial Ask for price
Description: Human GZMA knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Cell line gene knock-in and knock-out

S301 -
EUR 15000

Human GZMA knockdown cell line

ABC-KD6566 1 vial Ask for price
Description: Human GZMA knockdown cell line is engineered by our optimized transduction of the specific shRNA with lentivirus. Knockdown levels are determined via qRT-PCR. Gentaur offers generation of stable knockdown (RNAi) cell lines expressing shRNAs targeting genes of your interest.

Araf CRISPR Knocked out RAW264.7 Stable cell Cell Line (Mouse) T1-19

T9511 1x10^6 cells / 1.0 ml
EUR 3950

Araf CRISPR Knocked out RAW264.7 Stable cell Cell Line (Mouse) T3-3

T9529 1x10^6 cells/1.0ml
EUR 3950

SIRT1 Knockout Stable 293T Cell Line

T3176 1x10^6 cells / 1.0 ml
EUR 3950

T47D/GFP Cell Line

AKR-208 1 vial
EUR 686.4
Description: T47D/GFP Cell Line stably expresses GFP and otherwise exhibits the same characteristics of the parental cell line.

Stable Mouse Myeloid-derived Suppressor-like LAL Knock Out (HD1B) Cell Line

T3187 1x10^6 cells / 1.0 ml
EUR 3950

293T Cell Line

LV010 1x10^6
EUR 450

293T [HEK-293T] Cell Line

CL-0005 1×10⁶ cells/vial
EUR 420
Description: Homo sapiens, Human

Mouse NACC1 CRISPR Stable Knockout ID8 Cell Line - Clone T1-23

T6826 1x10^6 cells / 1.0 ml
EUR 3950

293T/17 Cell Line

CL-0469 1×10⁶ cells/vial
EUR 500
Description: Homo sapiens, Human

293T Cell Lysate (Human embryonic kidney cell line)

LF-R0006 200 ul
EUR 103.2
Description: 293T (Human embryonic kidney cell line) Whole Cell Lysate

BRCA1 CRISPR Stable Knockout Human Fibroblast Cell Line

T6245 1x10^6 cells / 1.0 ml
EUR 3950

Blank Promoter Stable Expressing Human 293T Cell Line

T9618 1x10^6 cells / 1.0 ml
EUR 3950

PTPRA CRISPR Knockout Immortalized Human Lung Fibroblast Cell Line

T6827 1x10^6 cells / 1.0 ml Ask for price

293AD Cell Line

AD-100 1 vial
EUR 365

293AAV Cell Line

AAV-100 1 vial
EUR 405

293LTV Cell Line

LTV-100 1 vial
EUR 405

293RTV Cell Line

RV-100 1 vial
EUR 405

Cas9 Expressing 293T Cell Line

T3251 1x10^6 cells / 1.0 ml
EUR 795

293/GFP Cell Line

AKR-200 1 vial
EUR 460

Human CRISP1 knockout cell line

ABC-KH3569 1 vial Ask for price
Description: Human CRISP1 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human CRISP2 knockout cell line

ABC-KH3570 1 vial Ask for price
Description: Human CRISP2 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human CRISP3 knockout cell line

ABC-KH3571 1 vial Ask for price
Description: Human CRISP3 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

A549/GFP Cell Line

AKR-209 1 vial
EUR 460

HeLa/GFP Cell Line

AKR-213 1 vial
EUR 460

293/Cas9 Cell Line

AKR-5110 1 vial
EUR 460

HeLa/Cas9 Cell Line

AKR-5111 1 vial
EUR 460

NIH3T3/GFP Cell Line

AKR-214 1 vial
EUR 460

Stable 293T-ATD cell line

T6340 1x10^6 cells / 1.0 ml
EUR 3950

NIH3T3/Cas9 Cell Line

AKR-5104 1 vial
EUR 460

Acan CRISPR Knockout RCS Cell Line (Rat)

T3000 1x10^6 cells / 1.0 ml Ask for price

PTPN6 Stable Knocked Out THP-1 Cell Line

T6216 1x10^6 cells / 1.0 ml
EUR 3950

Human CRISPLD1 knockout cell line

ABC-KH3572 1 vial Ask for price
Description: Human CRISPLD1 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human CRISPLD2 knockout cell line

ABC-KH3573 1 vial Ask for price
Description: Human CRISPLD2 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

MCF-7/Luc Cell Line

AKR-234 1 vial
EUR 686.4
Description: MCF-7/Luc Cell Line stably expresses luciferase and otherwise exhibits the same characteristics of the parental cell line.

SKOV-3/Luc Cell Line

AKR-232 1 vial
EUR 686.4
Description: SKOV-3/Luc Cell Line stably expresses luciferase and otherwise exhibits the same characteristics of the parental cell line.

OVCAR-5/RFP Cell Line

AKR-254 1 vial
EUR 686.4
Description: OVCAR-5/RFP Cell Line stably expresses RFP and otherwise exhibits the same characteristics of the parental cell line.

Human CRISP1 knockdown cell line

ABC-KD3569 1 vial Ask for price
Description: Human CRISP1 knockdown cell line is engineered by our optimized transduction of the specific shRNA with lentivirus. Knockdown levels are determined via qRT-PCR. Gentaur offers generation of stable knockdown (RNAi) cell lines expressing shRNAs targeting genes of your interest.

Human CRISP2 knockdown cell line

ABC-KD3570 1 vial Ask for price
Description: Human CRISP2 knockdown cell line is engineered by our optimized transduction of the specific shRNA with lentivirus. Knockdown levels are determined via qRT-PCR. Gentaur offers generation of stable knockdown (RNAi) cell lines expressing shRNAs targeting genes of your interest.

Human CRISP3 knockdown cell line

ABC-KD3571 1 vial Ask for price
Description: Human CRISP3 knockdown cell line is engineered by our optimized transduction of the specific shRNA with lentivirus. Knockdown levels are determined via qRT-PCR. Gentaur offers generation of stable knockdown (RNAi) cell lines expressing shRNAs targeting genes of your interest.

SIRT1 Wildtype Stable 293T Cell Line

T3175 1x10^6 cells / 1.0 ml
EUR 3950

TARGATT? Knock-in Mouse Cell Line Generation Kit (Master Cell Line)

AST-7001 1 Kit Ask for price
Description: 6 month

Human CRISPLD1 knockdown cell line

ABC-KD3572 1 vial Ask for price
Description: Human CRISPLD1 knockdown cell line is engineered by our optimized transduction of the specific shRNA with lentivirus. Knockdown levels are determined via qRT-PCR. Gentaur offers generation of stable knockdown (RNAi) cell lines expressing shRNAs targeting genes of your interest.

Human CRISPLD2 knockdown cell line

ABC-KD3573 1 vial Ask for price
Description: Human CRISPLD2 knockdown cell line is engineered by our optimized transduction of the specific shRNA with lentivirus. Knockdown levels are determined via qRT-PCR. Gentaur offers generation of stable knockdown (RNAi) cell lines expressing shRNAs targeting genes of your interest.

Human GZMB knockout cell line

ABC-KH6567 1 vial Ask for price
Description: Human GZMB knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human GZMH knockout cell line

ABC-KH6568 1 vial Ask for price
Description: Human GZMH knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human GZMK knockout cell line

ABC-KH6569 1 vial Ask for price
Description: Human GZMK knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human GZMM knockout cell line

ABC-KH6570 1 vial Ask for price
Description: Human GZMM knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

GFAT1 CRISPR Stable Knockout H1299 Cell Line

T6199 1x10^6 cells / 1.0 ml
EUR 3950

EDC4 CRISPR Stable Knockout HEK293T Cell Line

T6241 1x10^6 cells / 1.0 ml
EUR 3950

DJ-1 CRISPR Stable Knockout HeLa Cell Line

T6181 1x10^6 cells / 1.0 ml
EUR 3950

PGC-1α/ERRα Stable 293T Cell Line

T3060 1x10^6 cells / 1.0 ml
EUR 385

YBX1 Stable Knockout Human NK/T Cell Line #T3-16 P6

T9508 1x10^6 cells / 1.0 ml Ask for price

PDPN CRISPR Stable Knockout COS-7 Cell Line

T6039 1x10^6 cells / 1.0 ml
EUR 3950

PD-L1 CRISPR Stable Knockout CT26 Cell Line

T6237 1x10^6 cells / 1.0 ml
EUR 3950

PD-L1 CRISPR Stable Knockout MC38 Cell Line

T6149 1x10^6 cells / 1.0 ml
EUR 3950

LIMD1-/- CRISPR Stable Knockout HeLa Cell Line

T6357 1x10^6 cells / 1.0 ml
EUR 3950

Mouse R-spondin1 Stable 293T Cell Line

T3156 1x10^6 cells / 1.0 ml
EUR 3950

TARGATT? Knock-in iPSC Generation (Master Cell Line)

AST-1100 1 vial of 1X10^6 cells Ask for price
Description: 6 month

SLC35A1 CRISPR Stable Knockout CHO-S Cell Line

T6040 1x10^6 cells / 1.0 ml
EUR 3950

CXCL1 & CXCL8 CRISPR Double Knockout L3.6pl Cell Line

T6047 1x10^6 cells / 1.0 ml Ask for price

Human GZMB knockdown cell line

ABC-KD6567 1 vial Ask for price
Description: Human GZMB knockdown cell line is engineered by our optimized transduction of the specific shRNA with lentivirus. Knockdown levels are determined via qRT-PCR. Gentaur offers generation of stable knockdown (RNAi) cell lines expressing shRNAs targeting genes of your interest.

Human GZMH knockdown cell line

ABC-KD6568 1 vial Ask for price
Description: Human GZMH knockdown cell line is engineered by our optimized transduction of the specific shRNA with lentivirus. Knockdown levels are determined via qRT-PCR. Gentaur offers generation of stable knockdown (RNAi) cell lines expressing shRNAs targeting genes of your interest.

Human GZMK knockdown cell line

ABC-KD6569 1 vial Ask for price
Description: Human GZMK knockdown cell line is engineered by our optimized transduction of the specific shRNA with lentivirus. Knockdown levels are determined via qRT-PCR. Gentaur offers generation of stable knockdown (RNAi) cell lines expressing shRNAs targeting genes of your interest.

Human GZMM knockdown cell line

ABC-KD6570 1 vial Ask for price
Description: Human GZMM knockdown cell line is engineered by our optimized transduction of the specific shRNA with lentivirus. Knockdown levels are determined via qRT-PCR. Gentaur offers generation of stable knockdown (RNAi) cell lines expressing shRNAs targeting genes of your interest.

Platinum-E Retroviral Packaging Cell Line, Ecotropic

RV-101 1 vial
EUR 770

Platinum-GP Retroviral Packaging Cell Line, Pantropic

RV-103 1 vial
EUR 770

Platinum-A Retroviral Packaging Cell Line, Amphotropic

RV-102 1 vial
EUR 770

PFN2 Stable Expressing 293T Cell Line - Polyclonal

T9606 1x10^6 cells / 1.0 ml
EUR 3950

Total Protein - Murine Embryonic Stem Cell Line D3

CBA-305 500 ?g
EUR 414
Description:
  • Isolated from mouse ES-D3 cell line
  • Presented as 500 µg at 1 mg/mL in NP-40 Solubilization Buffer

PLN Knock-out Human Induced Pluripotent Stem Cells (Episomal, HFF)

iPS41 1 Vial
EUR 2268

AXL CRISPR Stable Knockout HT1080 (1-IV) Cell Line

T6232 1x10^6 cells / 1.0 ml
EUR 3950

AXL CRISPR Stable Knockout HT1080 (3-II) Cell Line

T6233 1x10^6 cells / 1.0 ml
EUR 3950

LRP1 Knock-out Human Induced Pluripotent Stem Cells (Episomal, HFF)

iPS31 1 Vial
EUR 2268

AFF2 Knock-out Human Induced Pluripotent Stem Cells (Episomal, HFF)

iPS61 1 Vial
EUR 2268

ABCA7 Knock-out Human Induced Pluripotent Stem Cells (Episomal, HFF)

iPS21 1 Vial
EUR 2268

KCNK3 Knock-out Human Induced Pluripotent Stem Cells (Episomal, HFF)

iPS51 1 Vial
EUR 2268

LLGL1 Knock-out Human Induced Pluripotent Stem Cells (Episomal, HFF)

iPS71 1 Vial
EUR 2268

TARGATT? Knock-in CHO Generation Kit (Master Cell Line)

AST-1200 1 Kit Ask for price
Description: 12 month

TARGATT? Knock-in HEK293 Generation Kit (Master Cell Line)

AST-1300 1 Kit Ask for price
Description: 12 month

GZMA 3'UTR GFP Stable Cell Line

TU059495 1.0 ml
EUR 1672.8

Gzma 3'UTR GFP Stable Cell Line

TU255597 1.0 ml Ask for price

Gzma 3'UTR GFP Stable Cell Line

TU159260 1.0 ml Ask for price

Human CRIM1 knockout cell line

ABC-KH3563 1 vial Ask for price
Description: Human CRIM1 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human CRIP1 knockout cell line

ABC-KH3564 1 vial Ask for price
Description: Human CRIP1 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human CRIP2 knockout cell line

ABC-KH3565 1 vial Ask for price
Description: Human CRIP2 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human CRIP3 knockout cell line

ABC-KH3566 1 vial Ask for price
Description: Human CRIP3 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human CRIPT knockout cell line

ABC-KH3568 1 vial Ask for price
Description: Human CRIPT knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human CRIPAK knockout cell line

ABC-KH3567 1 vial Ask for price
Description: Human CRIPAK knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Gzma 3'UTR Luciferase Stable Cell Line

TU205597 1.0 ml Ask for price

GZMA 3'UTR Luciferase Stable Cell Line

TU009495 1.0 ml
EUR 1672.8

Gzma 3'UTR Luciferase Stable Cell Line

TU109260 1.0 ml Ask for price

Human 293T Cell Lysate Lyophilized

IHU293TTLLY200UG each
EUR 89
Description: Human 293T Cell Lysate Lyophilized

Human 293T Cell Lysate Lyophilized

MBS136608-02mg 0.2mg
EUR 205

Human 293T Cell Lysate Lyophilized

MBS136608-5x02mg 5x0.2mg
EUR 745

AAVS1 Positive Control EGIP 293T Reporter Cell Line

CAS606A-1 1 Vial
EUR 726

GZMA sgRNA CRISPR Lentivector set (Human)

K0923801 3 x 1.0 ug
EUR 406.8

VEGF Promoter Stable Expressing 293T Cell Line - Clone #2

T9622 1x10^6 cells / 1.0 ml
EUR 3950

Human 293T Whole Cell Lysate

LYSATE0032 200ug
EUR 180
Description: This cell lysate is prepared from human 293T using Boster's RIPA Lysis Buffer (AR0105) using a standard whole cell lysate protocol. The concentration was determined using the BCA assay process and then diluted using Dithiothreitol (DTT) and a reducing SDS sample loading buffer, heated for 5 minutes at 100˚C.

Human CRIM1 knockdown cell line

ABC-KD3563 1 vial Ask for price
Description: Human CRIM1 knockdown cell line is engineered by our optimized transduction of the specific shRNA with lentivirus. Knockdown levels are determined via qRT-PCR. Gentaur offers generation of stable knockdown (RNAi) cell lines expressing shRNAs targeting genes of your interest.

Human CRIP1 knockdown cell line

ABC-KD3564 1 vial Ask for price
Description: Human CRIP1 knockdown cell line is engineered by our optimized transduction of the specific shRNA with lentivirus. Knockdown levels are determined via qRT-PCR. Gentaur offers generation of stable knockdown (RNAi) cell lines expressing shRNAs targeting genes of your interest.

Human CRIP2 knockdown cell line

ABC-KD3565 1 vial Ask for price
Description: Human CRIP2 knockdown cell line is engineered by our optimized transduction of the specific shRNA with lentivirus. Knockdown levels are determined via qRT-PCR. Gentaur offers generation of stable knockdown (RNAi) cell lines expressing shRNAs targeting genes of your interest.

Human CRIP3 knockdown cell line

ABC-KD3566 1 vial Ask for price
Description: Human CRIP3 knockdown cell line is engineered by our optimized transduction of the specific shRNA with lentivirus. Knockdown levels are determined via qRT-PCR. Gentaur offers generation of stable knockdown (RNAi) cell lines expressing shRNAs targeting genes of your interest.

Human CRIPT knockdown cell line

ABC-KD3568 1 vial Ask for price
Description: Human CRIPT knockdown cell line is engineered by our optimized transduction of the specific shRNA with lentivirus. Knockdown levels are determined via qRT-PCR. Gentaur offers generation of stable knockdown (RNAi) cell lines expressing shRNAs targeting genes of your interest.

hCETP shRNA (Target C) Knock Down THP-1 Cell Line-Polyclone

T9789 1x10^6 cells / 1.0 ml Ask for price

Human CRIPAK knockdown cell line

ABC-KD3567 1 vial Ask for price
Description: Human CRIPAK knockdown cell line is engineered by our optimized transduction of the specific shRNA with lentivirus. Knockdown levels are determined via qRT-PCR. Gentaur offers generation of stable knockdown (RNAi) cell lines expressing shRNAs targeting genes of your interest.

Human LIN37 knockout cell line

ABC-KH8476 1 vial Ask for price
Description: Human LIN37 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human GC knockout cell line

ABC-KH5948 1 vial Ask for price
Description: Human GC knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human GK knockout cell line

ABC-KH6087 1 vial Ask for price
Description: Human GK knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human HP knockout cell line

ABC-KH6972 1 vial Ask for price
Description: Human HP knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human HR knockout cell line

ABC-KH6992 1 vial Ask for price
Description: Human HR knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human KL knockout cell line

ABC-KH7942 1 vial Ask for price
Description: Human KL knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human KY knockout cell line

ABC-KH8250 1 vial Ask for price
Description: Human KY knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human MB knockout cell line

ABC-KH9065 1 vial Ask for price
Description: Human MB knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human F2 knockout cell line

ABC-KH5009 1 vial Ask for price
Description: Human F2 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human F3 knockout cell line

ABC-KH5014 1 vial Ask for price
Description: Human F3 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human F5 knockout cell line

ABC-KH5015 1 vial Ask for price
Description: Human F5 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human F7 knockout cell line

ABC-KH5016 1 vial Ask for price
Description: Human F7 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human F8 knockout cell line

ABC-KH5017 1 vial Ask for price
Description: Human F8 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human F9 knockout cell line

ABC-KH5021 1 vial Ask for price
Description: Human F9 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human AR knockout cell line

ABC-KH0856 1 vial Ask for price
Description: Human AR knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human SI knockout cell line

ABC-KH13776 1 vial Ask for price
Description: Human SI knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human T knockout cell line

ABC-KH15011 1 vial Ask for price
Description: Human T knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human TF knockout cell line

ABC-KH15318 1 vial Ask for price
Description: Human TF knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human TG knockout cell line

ABC-KH15342 1 vial Ask for price
Description: Human TG knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human TH knockout cell line

ABC-KH15368 1 vial Ask for price
Description: Human TH knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human PC knockout cell line

ABC-KH11173 1 vial Ask for price
Description: Human PC knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human XG knockout cell line

ABC-KH17067 1 vial Ask for price
Description: Human XG knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human XK knockout cell line

ABC-KH17074 1 vial Ask for price
Description: Human XK knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human CP knockout cell line

ABC-KH3480 1 vial Ask for price
Description: Human CP knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human CS knockout cell line

ABC-KH3611 1 vial Ask for price
Description: Human CS knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human C2 knockout cell line

ABC-KH1951 1 vial Ask for price
Description: Human C2 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human C3 knockout cell line

ABC-KH2027 1 vial Ask for price
Description: Human C3 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human C5 knockout cell line

ABC-KH2074 1 vial Ask for price
Description: Human C5 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human C6 knockout cell line

ABC-KH2100 1 vial Ask for price
Description: Human C6 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human C7 knockout cell line

ABC-KH2130 1 vial Ask for price
Description: Human C7 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human C9 knockout cell line

ABC-KH2174 1 vial Ask for price
Description: Human C9 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human CEL knockout cell line

ABC-KH2905 1 vial Ask for price
Description: Human CEL knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human LIN7A knockout cell line

ABC-KH8477 1 vial Ask for price
Description: Human LIN7A knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human LIN7B knockout cell line

ABC-KH8478 1 vial Ask for price
Description: Human LIN7B knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human LIN7C knockout cell line

ABC-KH8479 1 vial Ask for price
Description: Human LIN7C knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human LINS knockout cell line

ABC-KH8486 1 vial Ask for price
Description: Human LINS knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human LIN28A knockout cell line

ABC-KH8474 1 vial Ask for price
Description: Human LIN28A knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human LIN28B knockout cell line

ABC-KH8475 1 vial Ask for price
Description: Human LIN28B knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human NDN knockout cell line

ABC-KH9930 1 vial Ask for price
Description: Human NDN knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human NDP knockout cell line

ABC-KH9934 1 vial Ask for price
Description: Human NDP knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human NEB knockout cell line

ABC-KH9989 1 vial Ask for price
Description: Human NEB knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human FRK knockout cell line

ABC-KH5720 1 vial Ask for price
Description: Human FRK knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human FRY knockout cell line

ABC-KH5737 1 vial Ask for price
Description: Human FRY knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human FST knockout cell line

ABC-KH5752 1 vial Ask for price
Description: Human FST knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human FTL knockout cell line

ABC-KH5760 1 vial Ask for price
Description: Human FTL knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human FTO knockout cell line

ABC-KH5762 1 vial Ask for price
Description: Human FTO knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human FUK knockout cell line

ABC-KH5768 1 vial Ask for price
Description: Human FUK knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human FUS knockout cell line

ABC-KH5773 1 vial Ask for price
Description: Human FUS knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human FUZ knockout cell line

ABC-KH5784 1 vial Ask for price
Description: Human FUZ knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human FYB knockout cell line

ABC-KH5795 1 vial Ask for price
Description: Human FYB knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human FYN knockout cell line

ABC-KH5797 1 vial Ask for price
Description: Human FYN knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human GAA knockout cell line

ABC-KH5817 1 vial Ask for price
Description: Human GAA knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human GAK knockout cell line

ABC-KH5864 1 vial Ask for price
Description: Human GAK knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human GAL knockout cell line

ABC-KH5865 1 vial Ask for price
Description: Human GAL knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human GAN knockout cell line

ABC-KH5901 1 vial Ask for price
Description: Human GAN knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human GBA knockout cell line

ABC-KH5934 1 vial Ask for price
Description: Human GBA knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human GCA knockout cell line

ABC-KH5949 1 vial Ask for price
Description: Human GCA knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human GCG knockout cell line

ABC-KH5955 1 vial Ask for price
Description: Human GCG knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human GCK knockout cell line

ABC-KH5959 1 vial Ask for price
Description: Human GCK knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human GDA knockout cell line

ABC-KH5974 1 vial Ask for price
Description: Human GDA knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human GEM knockout cell line

ABC-KH5999 1 vial Ask for price
Description: Human GEM knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human GFY knockout cell line

ABC-KH6017 1 vial Ask for price
Description: Human GFY knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human GGH knockout cell line

ABC-KH6024 1 vial Ask for price
Description: Human GGH knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Lasă un răspuns

Adresa ta de email nu va fi publicată. Câmpurile obligatorii sunt marcate cu *