Specyficzna rekrutacja regulatorowych limfocytów T w raku jajnika

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Specyficzna rekrutacja regulatorowych limfocytów T w raku jajnika

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Płynny mannequin mozaiki struktury błon komórkowych.

 Este prezentat un mannequin de mozaic fluid pentru organizarea și structura brută a proteinelor și lipidelor membranelor biologice. Modelul este în concordanță cu restricțiile impuse de termodinamică. În acest mannequin, proteinele care fac parte integrantă din membrană sunt un set eterogen de molecule globulare, fiecare dispuse într-o structură amfipatică, adică cu grupările ionice și extrem de polare care ies din membrană în faza apoasă și grupurile nepolare. în mare măsură îngropat în interiorul hidrofob al membranei. Aceste molecule globulare sunt parțial încorporate într-o matrice de fosfolipide. Cea mai mare parte a fosfolipidelor este organizată ca un strat strat discontinuu, fluid, deși o mică parte a lipidei poate interacționa în mod particular cu proteinele de membrană.

Structura mozaicului fluid este, prin urmare, în mod formal similară cu o soluție bidimensională orientată de proteine ​​integrale (sau lipoproteine) în solventul bistrat cu fosfolipide vâscoase. Sunt descrise experimente recente cu o mare varietate de tehnici și mai multe sisteme de membrană diferite, toate acestea fiind compatibile cu modelul mozaicului fluid și îi adaugă multe detalii. Prin urmare, pare adecvat să sugerăm posibile mecanisme pentru diferite funcții ale membranei și fenomene mediate de membrană în lumina modelului. Ca exemple, sunt sugerate mecanisme testabile experimental pentru   modificările suprafeței celulare în transformarea malignă și pentru efectele de cooperare prezentate în interacțiunile membranelor cu unii liganzi specifici.

Notă adăugată în dovadă: De când a fost scris acest articol, am obținut dovezi microscopice electronice (69) conform cărora situsurile de legare a concanavalinei A pe membranele fibroblastelor de șoarece transformate de virusul SV40 ( celule 3T3  ) sunt mai grupate decât siturile de pe membranele celule normale  , după cum se prezice prin ipoteza reprezentată în Fig. 7B. A apărut și un studiu realizat de Taylor și colab. (70) care arată efectele remarcabile produse asupra  limfocitelor  prin adăugarea de anticorpi direcționați către moleculele lor de imunoglobulină de suprafață.

Anticorpii induc o redistribuire și pinocitoză a acestor imunoglobuline de suprafață, astfel încât în ​​aproximativ 30 de minute la 37 de grade C imunoglobulinele de suprafață sunt complet măturate din membrană. Aceste efecte nu apar, totuși, dacă anticorpii bivalenți sunt înlocuiți cu fragmentele lor Fab univalente sau dacă experimentele de anticorpi sunt efectuate la zero grade C în loc de 37 grade C.

Aceste și rezultatele conexe indică cu tărie că anticorpii bivalenți produc o agregare a moleculelor de imunoglobulină de suprafață în planul membranei, care pot apărea numai dacă moleculele de imunoglobulină sunt libere să difuzeze în membrană . Această agregare atuncipare să declanșeze pinocitoza componentelor membranei printr-un mecanism necunoscut. Astfel de transformări de membrană pot avea o importanță crucială în inducerea unui răspuns de anticorp la un antigen, precum și iv alte procese de   diferențiere celulară .

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TARGATT? Knock-in Mouse Cell Line Generation Kit (Master Cell Line)

AST-7001 1 Kit Ask for price
Description: 6 month

TARGATT? Knock-in CHO Generation Kit (Master Cell Line)

AST-1200 1 Kit Ask for price
Description: 12 month

TARGATT? Knock-in HEK293 Generation Kit (Master Cell Line)

AST-1300 1 Kit Ask for price
Description: 12 month

HEK-293T Telomerase Over-Expressing Cell Pellet

abx069991-1Pellet 1 Pellet
EUR 477.6

Basic HR Targeting Vector [MCS1-LoxP-MCS2-MCS3-pA-LoxP-MCS4] for Gene Knock-In/Out

HR100PA-1 10 ug
EUR 1125.6

Human Tyrosine-protein kinase Lck (LCK)

1-CSB-EP012806HU
  • EUR 456.00
  • EUR 256.80
  • EUR 1570.80
  • EUR 672.00
  • EUR 1047.60
  • EUR 314.40
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Human Tyrosine-protein kinase Lck(LCK) expressed in E.coli

Human Tyrosine-protein kinase Lck (LCK)

1-CSB-EP012806HUa2
  • EUR 456.00
  • EUR 256.80
  • EUR 1570.80
  • EUR 672.00
  • EUR 1047.60
  • EUR 314.40
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Human Tyrosine-protein kinase Lck(LCK) expressed in E.coli

293T Transfection Kit (1 mL)

P902 - Ask for price

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P902S - Ask for price

293T Transfection Kit (1 mL)

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P903S - Ask for price

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LCK 3'UTR Luciferase Stable Cell Line

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Gene Knock-Out HR Targeting Vector w/Single Selection Marker (Blasticidin) and Negative Selection (TK) Against Random Integration

HR720PA-1 10 µg
EUR 1374

293AAV Cell Line

AAV-100 1 vial
EUR 609.6
Description: The 293AAV Cell Line is derived from the parental 293 cells but selected for attributes that increase AAV production, including firmer attachment and larger surface area.

293AD Cell Line

AD-100 1 vial
EUR 553.2
Description: The 293AD Cell Line is derived from the parental 293 cells but selected for attributes that increase adenovirus production, including firmer attachment and larger surface area.

293LTV Cell Line

LTV-100 1 vial
EUR 609.6
Description: The 293LTV Cell Line is derived from the parental 293 cells but selected for attributes that increase lentiviral production, including fimrer attachment and larger surface area.

293RTV Cell Line

RV-100 1 vial
EUR 609.6
Description: The 293RTV Cell Line is derived from the parental 293 cells but selected for attributes that increase retroviral production, including fimrer attachment and larger surface area.

Lck/ Rat Lck ELISA Kit

ELI-38801r 96 Tests
EUR 1063.2

LCK sgRNA CRISPR Lentivector set (Human)

K1201901 3 x 1.0 ug
EUR 406.8

Human Tyrosine- protein kinase Lck, LCK ELISA KIT

ELI-31641h 96 Tests
EUR 988.8

Human Tyrosine protein kinase Lck(LCK) ELISA kit

E01T0623-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Human Tyrosine protein kinase Lck(LCK) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Tyrosine protein kinase Lck(LCK) ELISA kit

E01T0623-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Human Tyrosine protein kinase Lck(LCK) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Tyrosine protein kinase Lck(LCK) ELISA kit

E01T0623-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Human Tyrosine protein kinase Lck(LCK) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Gene Knock-Out HR Targeting Vector w/Dual Selection Markers (GFP+Puro) and Negative Selection (TK) Against Random Integration

HR700PA-1 10 µg
EUR 1374

Gene Knock-Out HR Targeting Vector w/Dual Selection Markers (RFP+Hygro) and Negative Selection (TK) Against Random Integration

HR710PA-1 10 µg
EUR 1374

TARGATT? Knock-in iPSC Genotyping Kit

AST-1102 1 Kit Ask for price
Description: 12 month

293/GFP Cell Line

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EUR 686.4
Description: 293/GFP Cell Line stably expresses GFP and otherwise exhibits the same characteristics of the parental cell line.

T47D/GFP Cell Line

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EUR 686.4
Description: T47D/GFP Cell Line stably expresses GFP and otherwise exhibits the same characteristics of the parental cell line.

A549/GFP Cell Line

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EUR 686.4
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HeLa/GFP Cell Line

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EUR 686.4
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NIH3T3/GFP Cell Line

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EUR 686.4
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NIH3T3/Cas9 Cell Line

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293/Cas9 Cell Line

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HeLa/Cas9 Cell Line

AKR-5111 1 vial
EUR 686.4

Monoclonal p56lck / LCK Antibody (clone Lck-01), Clone: Lck-01

APR17729G 0.05mg
EUR 580.8
Description: A Monoclonal antibody against Human p56lck / LCK (clone Lck-01). The antibodies are raised in Mouse and are from clone Lck-01. This antibody is applicable in WB and IHC-P, ICC, IP, Flo

Tyrosine-Protein Kinase Lck (LCK) Antibody

abx159593-100ul 100 ul
EUR 560.4

Microplate Swing-Out Centrifuge

abx725026-1Unit 1 Unit
EUR 1771.2

Clinical Swing-Out Centrifuge

abx725027-1Unit 1 Unit
EUR 1771.2

Lck antibody

70R-11874 100 ug
EUR 483.6
Description: Rabbit polyclonal Lck antibody

LCK Peptide

42-990P 0.1 mg
EUR 405.6
Description: LCK Peptide

LCK antibody

70R-49992 100 ul
EUR 344.4
Description: Purified Polyclonal LCK antibody

LCK antibody

70R-49993 100 ul
EUR 292.8
Description: Purified Polyclonal LCK antibody

LCK antibody

70R-2658 50 ug
EUR 560.4
Description: Rabbit polyclonal LCK antibody raised against the N terminal of LCK

Lck antibody

70R-34247 100 ug
EUR 392.4
Description: Rabbit polyclonal Lck antibody

LCK antibody

70R-34386 100 ug
EUR 392.4
Description: Rabbit polyclonal LCK antibody

Lck antibody

70R-35606 100 ug
EUR 392.4
Description: Rabbit polyclonal Lck antibody

Lck antibody

70R-36662 100 ug
EUR 392.4
Description: Rabbit Polyclonal Lck antibody

LCK antibody

70R-18229 50 ul
EUR 522
Description: Rabbit polyclonal LCK antibody

LCK Antibody

32644-100ul 100ul
EUR 302.4

Lck protein

30R-2848 5 ug
EUR 603.6
Description: Purified recombinant Human Lck protein

Lck Antibody

35363-100ul 100ul
EUR 468

Lck Antibody

35446-100ul 100ul
EUR 468

Lck Antibody

3498-100
EUR 379.2

Lck Antibody

3498-30T
EUR 175.2

LCK antibody

20R-2987 100 ul
EUR 471.6
Description: Rabbit polyclonal LCK antibody

LCK antibody

10R-10823 100 ug
EUR 457.2
Description: Mouse monoclonal LCK antibody

LCK antibody

10R-8607 100 ul
EUR 471.6
Description: Mouse monoclonal LCK antibody

LCK antibody

10R-8608 100 ul
EUR 471.6
Description: Mouse monoclonal LCK antibody

Lck antibody

20R-1612 100 ug
EUR 807.6
Description: Rabbit polyclonal Lck antibody

Lck antibody

20R-1613 100 ug
EUR 846
Description: Rabbit polyclonal Lck antibody

LCK antibody

20R-1997 50 ug
EUR 337.2
Description: Rabbit polyclonal LCK antibody

LCK antibody

20R-2166 50 ug
EUR 337.2
Description: Rabbit polyclonal LCK antibody

LCK antibody

10R-2019 100 ul
EUR 522
Description: Mouse monoclonal LCK antibody

LCK Antibody

ABF5412 100 ug
EUR 525.6

Lck Antibody

ABF6100 100 ug
EUR 525.6

Lck Antibody

ABF6101 100 ug
EUR 525.6

LCK Antibody

ABD6900 100 ug
EUR 525.6

Lck Inhibitor

A3539-1 1 mg
EUR 184.8
Description: Lck Inhibitor is a small-molecule inhibitor of with IC50 value of 7 nM [1].The lymphocyte specific kinase which expressed in NK cells and T-cells is a member of the Src kinase family.

Lck Inhibitor

A3539-5 5 mg
EUR 266.4
Description: Lck Inhibitor is a small-molecule inhibitor of with IC50 value of 7 nM [1].The lymphocyte specific kinase which expressed in NK cells and T-cells is a member of the Src kinase family.

LCK siRNA

20-abx902944
  • EUR 661.20
  • EUR 878.40
  • 15 nmol
  • 30 nmol

LCK siRNA

20-abx922340
  • EUR 661.20
  • EUR 878.40
  • 15 nmol
  • 30 nmol

LCK siRNA

20-abx922341
  • EUR 661.20
  • EUR 878.40
  • 15 nmol
  • 30 nmol

Lck, Active

7733-5
EUR 444

Lck Antibody

AF7694 200ul
EUR 540

Lck Antibody

AF7695 200ul
EUR 540

LCK Antibody

AF7696 200ul
EUR 540

Lck Antibody

BF0456 200ul
EUR 540

LCK Antibody

DF6900 200ul
EUR 420

LCK Antibody

AF5412 200ul
EUR 420

Lck Antibody

AF6100 200ul
EUR 420

Lck Antibody

AF6101 200ul
EUR 420

LCK Antibody

1-CSB-PA012806GA01HU
  • EUR 716.40
  • EUR 399.60
  • 150ul
  • 50ul
Description: A polyclonal antibody against LCK. Recognizes LCK from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC

LCK Antibody

1-CSB-PA012806LA01HU
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against LCK. Recognizes LCK from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC, IF, IP; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200, IP:1:200-1:2000

LCK Antibody

1-CSB-PA003142
  • EUR 266.40
  • EUR 234.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against LCK. Recognizes LCK from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: WB, ELISA;WB:1/500-1/2000.ELISA:1/40000

LCK Antibody

1-CSB-PA009795
  • EUR 266.40
  • EUR 234.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against LCK. Recognizes LCK from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: WB, IHC, IF, ELISA;WB:1/500-1/2000.IHC:1/100-1/300.IF:1/200-1/1000.ELISA:1/5000

LCK Antibody

1-CSB-PA009798
  • EUR 266.40
  • EUR 234.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against LCK. Recognizes LCK from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: WB, IF, ELISA;WB:1/500-1/2000.IF:1/200-1/1000.ELISA:1/40000

LCK Antibody

1-CSB-PA009802
  • EUR 266.40
  • EUR 234.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against LCK. Recognizes LCK from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: WB, IF, ELISA;WB:1/500-1/2000.IF:1/200-1/1000.ELISA:1/5000

anti-LCK

LF-PA0206 100 ul
EUR 400.8
Description: Rabbit polyclonal to LCK

Lck Inhibitor

HY-12072 100mg
EUR 2422.8

anti-Lck

YF-PA12927 100 ug
EUR 483.6
Description: Rabbit polyclonal to Lck

LCK Antibody

R31894 100 ug
EUR 419

LCK Antibody

R35690-100UG 100 ug
EUR 399

LCK Antibody

RQ5136 100ul
EUR 419

LCK Antibody

F50711-0.08ML 0.08 ml
EUR 165

LCK Antibody

F50711-0.4ML 0.4 ml
EUR 379

LCK Antibody

F53783-0.1ML 0.1 ml
EUR 389

LCK Antibody

F54482-0.05ML 0.05 ml
EUR 165

LCK Antibody

F54482-0.2ML 0.2 ml
EUR 379

Lck Antibody

F43568-0.08ML 0.08 ml
EUR 165

Lck Antibody

F43568-0.4ML 0.4 ml
EUR 379

LCK Antibody

F48246-0.08ML 0.08 ml
EUR 165

LCK Antibody

F48246-0.4ML 0.4 ml
EUR 389

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HR210PA-1 10 ug
EUR 1374

Human LCK shRNA Plasmid

20-abx952664
  • EUR 961.20
  • EUR 1345.20
  • 150 µg
  • 300 µg

LCK ELISA KIT|Human

EF010640 96 Tests
EUR 826.8

SKOV-3/Luc Cell Line

AKR-232 1 vial
EUR 686.4
Description: SKOV-3/Luc Cell Line stably expresses luciferase and otherwise exhibits the same characteristics of the parental cell line.

MCF-7/Luc Cell Line

AKR-234 1 vial
EUR 686.4
Description: MCF-7/Luc Cell Line stably expresses luciferase and otherwise exhibits the same characteristics of the parental cell line.

OVCAR-5/RFP Cell Line

AKR-254 1 vial
EUR 686.4
Description: OVCAR-5/RFP Cell Line stably expresses RFP and otherwise exhibits the same characteristics of the parental cell line.

LCK sgRNA CRISPR Lentivector (Human) (Target 1)

K1201902 1.0 ug DNA
EUR 184.8

LCK sgRNA CRISPR Lentivector (Human) (Target 2)

K1201903 1.0 ug DNA
EUR 184.8

LCK sgRNA CRISPR Lentivector (Human) (Target 3)

K1201904 1.0 ug DNA
EUR 184.8

TARGATT? Knock-in iPSC Quick Knockin Kit

AST-1101 1 Kit Ask for price
Description: 12 month

Lck Colorimetric Cell-Based ELISA Kit

EKC1338 100ul
EUR 686.4

Human Proto-Oncogene Tyrosine-Protein Kinase LCK (LCK) ELISA Kit

abx388241-96tests 96 tests
EUR 1093.2

PinPoint-FC 293T Platform Cell Line for Targeted Gene Insertion (with PinPoint site already placed)

PIN320A-1 >2x10^5 cells
EUR 3724.8

Sierocy receptor jądrowy RORgammat kieruje programem różnicowania prozapalnych komórek pomocniczych IL-17 + T.

IL-17-T producătoare  de limfocite  au fost current dovedit a cuprinde o descendență distinctă de T helper proinflamatorii  celule , numite Th17  celule , care sunt o contributie majora la boli autoimune. Arătăm aici că receptorul nuclear orfan RORgammat este factorul cheie de transcripție care orchestrează diferențierea acestei  linii de celule efectoare  . RORgammat induce transcripția genelor care codifică IL-17 și IL-citokina înrudit 17F în naivi CD4 (+) T helper  celule  și este necesar pentru exprimarea lor ca răspuns la IL-6 și TGF-beta, citokinele cunoscute de a induce IL- 17.

Celulele Th17   sunt prezente în mod constitutiv în toată lamina propria intestinală, exprimă RORgammat și sunt absente la șoareci cu deficit de RORgammat sau IL-6. Șoarecii cu celule T cu deficit de RORgammat   au boli autoimune atenuate și nu au celule Th17 care se infiltrează în țesuturi  . Împreună, aceste studii sugerează că RORgammat este un regulator cheie al homeostaziei imune și evidențiază potențialul său ca țintă terapeutică în bolile inflamatorii.

Specyficzna rekrutacja regulatorowych limfocytów T w raku jajnika sprzyja przywilejowi immunologicznemu i pozwala przewidzieć skrócenie czasu przeżycia.

 

T de reglementare (T (REG))  Celulele  mediază toleranță periferică homeostatic prin suprimarea T autoreactive  celule . Nerespectarea imunității antitumorale gazdă poate fi cauzată de supresia exagerată antigen reactive asociate tumorii  limfocite  mediate de T (REG)  celule ; Cu toate acestea, dovezi definitive care (REG) T  celule  au un rol imunopatologice in cancerul uman este lipsit. Aici ne arată, în studii detaliate ale CD4 (+) CD25 (+) FOXP3 (+) T (REG)  celule  in 104 persoane afectate cu carcinom ovarian, tumoarea umană T (REG)  celule  suprima T-tumorale specifice  celulei  imunitate și contribuie la creșterea tumorilor umane in vivo.

De asemenea, arătăm că celulele T (reg)  tumorale  sunt asociate cu un risc crescut de deces și supraviețuire redusă. Celulele T (reg)  umane  se deplasează și se acumulează preferențial în tumori și ascită, dar rareori intră în ganglionii limfatici care drenează în stadiile ulterioare ale cancerului.

Celulele tumorale   și macrofagele microambientale produc chemokina CCL22, care mediază traficul de celule T (reg)   către tumoră. Această recrutare specifică a celulelor T (reg)   reprezintă un mecanism prin care tumorile pot favoriza privilegiul imunitar. Astfel, blocarea  migrației sau funcției celulelor T (reg)  poate ajuta la înfrângerea cancerului uman.

Przywracanie funkcji wyczerpanych limfocytów T CD8 podczas przewlekłej infekcji wirusowej

Afectarea funcțională a celulelor T specifice antigenului   este o caracteristică definitorie a multor infecții cronice, dar mecanismele de bază ale  disfuncției celulelor T nu sunt bine înțelese. Pentru a rezolva această problemă, am analizat genele exprimate in afectarea useful virus-specific T CD8  celule  prezente la șoarecii infectați cronic cu virusul coriomeningitei limfocitare (LCMV) și a comparat aceste cu profilul genetic al T CD8 memorie functionale  celule .

Aici raportăm că PD-1 (moartea programată 1; cunoscut și sub numele de Pdcd1) a fost selectiv reglat în sus de celulele T epuizate și că administrarea in vivo a anticorpilor care a blocat interacțiunea acestui receptor inhibitor cu ligandul său, PD-L1 (cunoscut și ca B7-H1), a îmbunătățit  răspunsurile celulelor T.

In particular, am constatat ca , chiar si la soareci persistent infectate care au fost lipsite de celule CD4 T de celule de  ajutor, blocarea PD-1 / PD-L1 cale de inhibare a avut un efect benefic asupra „neajutorat“ T CD8  celule , restabilind capacitatea lor de a suferi proliferare , secretă citokine, ucid celulele infectate   și scad încărcătura virală. Blocarea căii inhibitoare a CTLA-4 ( proteina Four asociată cu limfocitele T citotoxice ) nu a avut niciun efect nici asupra  funcției celulelor T , nici asupra controlului viral. Aceste studii identifică un mecanism particular de  epuizare a celulelor T și definesc o strategie imunologică potențial eficientă pentru tratamentul infecțiilor virale cronice.

Mouse Granzyme A (GZMA) ELISA Kit

RDR-GZMA-Mu-48Tests 48 Tests
EUR 613.2

Mouse Granzyme A (GZMA) ELISA Kit

RDR-GZMA-Mu-96Tests 96 Tests
EUR 850.8

Mouse Granzyme A (GZMA) ELISA Kit

RD-GZMA-Mu-48Tests 48 Tests
EUR 586.8

Mouse Granzyme A (GZMA) ELISA Kit

RD-GZMA-Mu-96Tests 96 Tests
EUR 812.4

AAVS1 Positive Control EGIP 293T Reporter Cell Line

CAS606A-1 1 Vial
EUR 968.4

HEK-293T cells

T0011002 One Frozen vial
EUR 546

Gene Knock-Out HR Targeting Vector [MCS1-EF1?-RFP-T2A-Puro-pA-MCS2]

HR110PA-1 10 ug
EUR 1227.6

Gene Knock-Out HR Targeting Vector [MCS1-EF1a-GFP-T2A-Puro-pA-MCS2]

HR410PA-1 10 ug
EUR 1227.6

Gene Knock-Out HR Targeting Vector [MCS1-EF1a-RFP-T2A-Hygro-pA-MCS2]

HR510PA-1 10 ug
EUR 1227.6

TARGATT? Knock-in iPSC Generation (Master Cell Line)

AST-1100 1 vial of 1X10^6 cells Ask for price
Description: 6 month

TARGATT? Knock-in Mouse Cell Line Generation Kit (Master Cell Line)

AST-7001 1 Kit Ask for price
Description: 6 month

TARGATT? Knock-in CHO Generation Kit (Master Cell Line)

AST-1200 1 Kit Ask for price
Description: 12 month

TARGATT? Knock-in HEK293 Generation Kit (Master Cell Line)

AST-1300 1 Kit Ask for price
Description: 12 month

HEK-293T Telomerase Over-Expressing Cell Pellet

abx069991-1Pellet 1 Pellet
EUR 477.6

GZMA 3'UTR Luciferase Stable Cell Line

TU009495 1.0 ml
EUR 1672.8

Gzma 3'UTR GFP Stable Cell Line

TU255597 1.0 ml Ask for price

GZMA 3'UTR GFP Stable Cell Line

TU059495 1.0 ml
EUR 1672.8

Gzma 3'UTR Luciferase Stable Cell Line

TU205597 1.0 ml Ask for price

Gzma 3'UTR Luciferase Stable Cell Line

TU109260 1.0 ml Ask for price

Gzma 3'UTR GFP Stable Cell Line

TU159260 1.0 ml Ask for price

Basic HR Targeting Vector [MCS1-LoxP-MCS2-MCS3-pA-LoxP-MCS4] for Gene Knock-In/Out

HR100PA-1 10 ug
EUR 1125.6

293T Transfection Kit (1 mL)

P902 - Ask for price

293T Transfection Kit (0.2 mL)

P902S - Ask for price

293T Transfection Kit (1 mL)

P903 - Ask for price

293T Transfection Kit (0.2 mL)

P903S - Ask for price

GZMA sgRNA CRISPR Lentivector set (Human)

K0923801 3 x 1.0 ug
EUR 406.8

GZMA Peptide

42-290P 0.1 mg
EUR 405.6
Description: (IN) GZMA Peptide

GZMA antibody

70R-17667 50 ul
EUR 522
Description: Rabbit polyclonal GZMA antibody

GZMA Antibody

ABD9054 100 ug
EUR 525.6

GZMA antibody

70R-9289 50 ug
EUR 560.4
Description: Affinity purified rabbit polyclonal GZMA antibody

GZMA siRNA

20-abx918982
  • EUR 661.20
  • EUR 878.40
  • 15 nmol
  • 30 nmol

GZMA siRNA

20-abx918983
  • EUR 661.20
  • EUR 878.40
  • 15 nmol
  • 30 nmol

GZMA Antibody

1-CSB-PA009084
  • EUR 266.40
  • EUR 234.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against GZMA. Recognizes GZMA from Human. This antibody is Unconjugated. Tested in the following application: IHC, IF, ELISA;IHC:1/100-1/300.IF:1/200-1/1000.ELISA:1/5000

GZMA Antibody

1-CSB-PA010081ESR2HU
  • EUR 266.40
  • EUR 402.00
  • 100ul
  • 50ul
Description: A polyclonal antibody against GZMA. Recognizes GZMA from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC; Recommended dilution: IHC:1:20-1:200

GZMA Antibody

1-CSB-PA010081GA01HU
  • EUR 716.40
  • EUR 399.60
  • 150ul
  • 50ul
Description: A polyclonal antibody against GZMA. Recognizes GZMA from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC

Gzma Antibody

1-CSB-PA010081LA01MO
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against Gzma. Recognizes Gzma from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB; Recommended dilution: WB:1:500-1:5000

GZMA Antibody

DF9054 200ul
EUR 420

Gene Knock-Out HR Targeting Vector w/Single Selection Marker (Blasticidin) and Negative Selection (TK) Against Random Integration

HR720PA-1 10 µg
EUR 1374

Human GZMA shRNA Plasmid

20-abx952036
  • EUR 961.20
  • EUR 1345.20
  • 150 µg
  • 300 µg

GZMA ELISA KIT|Human

EF000669 96 Tests
EUR 826.8

Human GZMA ELISA Kit

ELA-E0599h 96 Tests
EUR 988.8

GZMA Recombinant Protein (Human)

RP014302 100 ug Ask for price

293AAV Cell Line

AAV-100 1 vial
EUR 609.6
Description: The 293AAV Cell Line is derived from the parental 293 cells but selected for attributes that increase AAV production, including firmer attachment and larger surface area.

293AD Cell Line

AD-100 1 vial
EUR 553.2
Description: The 293AD Cell Line is derived from the parental 293 cells but selected for attributes that increase adenovirus production, including firmer attachment and larger surface area.

293LTV Cell Line

LTV-100 1 vial
EUR 609.6
Description: The 293LTV Cell Line is derived from the parental 293 cells but selected for attributes that increase lentiviral production, including fimrer attachment and larger surface area.

293RTV Cell Line

RV-100 1 vial
EUR 609.6
Description: The 293RTV Cell Line is derived from the parental 293 cells but selected for attributes that increase retroviral production, including fimrer attachment and larger surface area.

GZMA sgRNA CRISPR Lentivector (Human) (Target 1)

K0923802 1.0 ug DNA
EUR 184.8

GZMA sgRNA CRISPR Lentivector (Human) (Target 2)

K0923803 1.0 ug DNA
EUR 184.8

GZMA sgRNA CRISPR Lentivector (Human) (Target 3)

K0923804 1.0 ug DNA
EUR 184.8

Gene Knock-Out HR Targeting Vector w/Dual Selection Markers (GFP+Puro) and Negative Selection (TK) Against Random Integration

HR700PA-1 10 µg
EUR 1374

Gene Knock-Out HR Targeting Vector w/Dual Selection Markers (RFP+Hygro) and Negative Selection (TK) Against Random Integration

HR710PA-1 10 µg
EUR 1374

TARGATT? Knock-in iPSC Genotyping Kit

AST-1102 1 Kit Ask for price
Description: 12 month

293/GFP Cell Line

AKR-200 1 vial
EUR 686.4
Description: 293/GFP Cell Line stably expresses GFP and otherwise exhibits the same characteristics of the parental cell line.

T47D/GFP Cell Line

AKR-208 1 vial
EUR 686.4
Description: T47D/GFP Cell Line stably expresses GFP and otherwise exhibits the same characteristics of the parental cell line.

A549/GFP Cell Line

AKR-209 1 vial
EUR 686.4
Description: A549/GFP Cell Line stably expresses GFP and otherwise exhibits the same characteristics of the parental cell line.

HeLa/GFP Cell Line

AKR-213 1 vial
EUR 686.4
Description: HeLa/GFP Cell Line stably expresses GFP and otherwise exhibits the same characteristics of the parental cell line.

NIH3T3/GFP Cell Line

AKR-214 1 vial
EUR 686.4
Description: NIH3T3/GFP Cell Line stably expresses GFP and otherwise exhibits the same characteristics of the parental cell line.

NIH3T3/Cas9 Cell Line

AKR-5104 1 vial
EUR 686.4

293/Cas9 Cell Line

AKR-5110 1 vial
EUR 686.4

HeLa/Cas9 Cell Line

AKR-5111 1 vial
EUR 686.4

GZMA Polyclonal Antibody

42195-100ul 100ul
EUR 399.6

GZMA Blocking Peptide

33R-5360 100 ug
EUR 216
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of GZMA antibody, catalog no. 70R-9289

GZMA Rabbit pAb

A6231-100ul 100 ul
EUR 369.6

GZMA Rabbit pAb

A6231-200ul 200 ul
EUR 550.8

GZMA Rabbit pAb

A6231-20ul 20 ul
EUR 219.6

GZMA Rabbit pAb

A6231-50ul 50 ul
EUR 267.6

GZMA cloning plasmid

CSB-CL010081HU-10ug 10ug
EUR 279.6
Description: A cloning plasmid for the GZMA gene.

GZMA Blocking Peptide

DF9054-BP 1mg
EUR 234

Anti-GZMA antibody

STJ27987 100 µl
EUR 332.4
Description: Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here is a T cell- and natural killer cell-specific serine protease that may function as a common component necessary for lysis of target cells by cytotoxic T lymphocytes and natural killer cells.

Anti-GZMA antibody

STJ71899 100 µg
EUR 312

Anti-GZMA (4C6)

YF-MA20335 100 ug
EUR 435.6
Description: Mouse monoclonal to GZMA

Gzma Polyclonal Antibody

A59334-020 20 ul Ask for price

Gzma Polyclonal Antibody

A59334-050 50 ul Ask for price

Gzma Polyclonal Antibody

A59334-100 100 ul
EUR 423.5

Gzma Polyclonal Antibody

A59334
  • EUR 684.66
  • Ask for price
  • Ask for price
  • EUR 423.50
  • 100 µg
  • 20 ul
  • 50 ul
  • 100 ul

Microplate Swing-Out Centrifuge

abx725026-1Unit 1 Unit
EUR 1771.2

Clinical Swing-Out Centrifuge

abx725027-1Unit 1 Unit
EUR 1771.2

Gene Knock-Out HR Targeting Vector with TK selection [MCS1-LoxP-EF1?-GFP-T2A-Puro-P2A-hsvTK-pA-LoxP-MCS2]

HR210PA-1 10 ug
EUR 1374

Human Granzyme A (GZMA) Protein

20-abx653630
  • EUR 693.60
  • EUR 309.60
  • EUR 2064.00
  • EUR 828.00
  • EUR 510.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Human Granzyme A (GZMA) Protein

20-abx653632
  • EUR 1062.00
  • EUR 393.60
  • EUR 3400.80
  • EUR 1262.40
  • EUR 727.20
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Human Granzyme A (GZMA) Protein

20-abx651491
  • EUR 878.40
  • EUR 343.20
  • EUR 2766.00
  • EUR 1062.00
  • EUR 627.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

GZMA ELISA Kit (Human) (OKBB00906)

OKBB00906 96 Wells
EUR 606
Description: Description of target: Granzyme A is a protein that in humans is encoded by the GZMA gene. Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface "nonself" antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here is a T cell- and natural killer cell-specific serine protease that may function as a common component necessary for lysis of target cells by cytotoxic T lymphocytes and natural killer cells. GZMA induces caspase-independent apoptosis in a characteristic manner, except it causes a distinctive form of DNA damage: single-stranded DNA nicking. A target of GZMA is the SET complex, including HMGB2 and ANP32A.;Species reactivity: Human;Application: ELISA;Assay info: ;Sensitivity: <10pg/ml

GZMA ELISA Kit (Human) (OKAN05337)

OKAN05337 96 Wells
EUR 950.4
Description: Description of target: Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here is a T cell- and natural killer cell-specific serine protease that may function as a common component necessary for lysis of target cells by cytotoxic T lymphocytes and natural killer cells.;Species reactivity: Human;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.055 ng/mL

GZMA ORF Vector (Human) (pORF)

ORF004768 1.0 ug DNA
EUR 114

GZMA ELISA Kit (Human) (OKCD05260)

OKCD05260 96 Wells
EUR 1170
Description: Description of target: Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here is a T cell- and natural killer cell-specific serine protease that may function as a common component necessary for lysis of target cells by cytotoxic T lymphocytes and natural killer cells. Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here is a T cell- and natural killer cell-specific serine protease that may function as a common component necessary for lysis of target cells by cytotoxic T lymphocytes and natural killer cells. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.;Species reactivity: Human;Application: ELISA;Assay info: ;Sensitivity: < 5.7pg/mL

GZMA ELISA Kit (Human) (OKCD06562)

OKCD06562 96 Wells
EUR 903.6
Description: Description of target: Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here is a T cell- and natural killer cell-specific serine protease that may function as a common component necessary for lysis of target cells by cytotoxic T lymphocytes and natural killer cells. Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here is a T cell- and natural killer cell-specific serine protease that may function as a common component necessary for lysis of target cells by cytotoxic T lymphocytes and natural killer cells. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.;Species reactivity: Human;Application: ELISA;Assay info: ;Sensitivity: < 0.055ng/mL

Gzma sgRNA CRISPR Lentivector set (Rat)

K7364801 3 x 1.0 ug
EUR 406.8

Gzma sgRNA CRISPR Lentivector set (Mouse)

K3890501 3 x 1.0 ug
EUR 406.8

SKOV-3/Luc Cell Line

AKR-232 1 vial
EUR 686.4
Description: SKOV-3/Luc Cell Line stably expresses luciferase and otherwise exhibits the same characteristics of the parental cell line.

MCF-7/Luc Cell Line

AKR-234 1 vial
EUR 686.4
Description: MCF-7/Luc Cell Line stably expresses luciferase and otherwise exhibits the same characteristics of the parental cell line.

OVCAR-5/RFP Cell Line

AKR-254 1 vial
EUR 686.4
Description: OVCAR-5/RFP Cell Line stably expresses RFP and otherwise exhibits the same characteristics of the parental cell line.

TARGATT? Knock-in iPSC Quick Knockin Kit

AST-1101 1 Kit Ask for price
Description: 12 month

PinPoint-FC 293T Platform Cell Line for Targeted Gene Insertion (with PinPoint site already placed)

PIN320A-1 >2x10^5 cells
EUR 3724.8

Swing-out rotor 6-place

CEN0179 EACH
EUR 607.62

Swing-out rotor 8-place

CEN0180 EACH
EUR 701.1

Swing-out rotor 12-place

CEN0181 EACH
EUR 531.24

Rotor Swing out 6x5ml RB

CEN2634 EACH
EUR 429.78

Rotor Swing out 2x3MTP ID

CEN2664 EACH
EUR 1299.6

Autoclave Print-Out PAPER CR70

SXP374 EACH
EUR 40.7

Granzyme A (GZMA) Antibody

20-abx100560
  • EUR 493.20
  • EUR 159.60
  • EUR 1362.00
  • EUR 661.20
  • EUR 376.80
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Granzyme A (GZMA) Antibody

20-abx006330
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Granzyme A (GZMA) Antibody

abx122954-100ug 100 ug
EUR 469.2

Granzyme A (GZMA) Antibody

20-abx128528
  • EUR 477.60
  • EUR 159.60
  • EUR 1312.80
  • EUR 644.40
  • EUR 376.80
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Granzyme A (GZMA) Antibody

20-abx112843
  • EUR 878.40
  • EUR 477.60
  • 150 ul
  • 50 ul

Granzyme A (GZMA) Antibody

20-abx320202
  • EUR 360.00
  • EUR 292.80
  • 100 ul
  • 50 ul

Granzyme A (GZMA) Antibody

20-abx323175
  • EUR 376.80
  • EUR 292.80
  • 100 ug
  • 50 ug

Granzyme A (Gzma) Antibody

20-abx319042
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Granzyme A (GZMA) Antibody

abx432781-200ul 200 ul
EUR 343.2

Granzyme A (GZMA) Antibody

abx233633-100ug 100 ug
EUR 661.2

Granzyme A (GZMA) Antibody

20-abx176698
  • EUR 477.60
  • EUR 159.60
  • EUR 1312.80
  • EUR 644.40
  • EUR 376.80
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Granzyme A (GZMA) Antibody

20-abx176699
  • EUR 477.60
  • EUR 159.60
  • EUR 1312.80
  • EUR 644.40
  • EUR 376.80
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Granzyme A (GZMA) Antibody

20-abx176701
  • EUR 1362.00
  • EUR 661.20
  • 1 mg
  • 200 ug

Mouse Granzyme A (Gzma)

1-CSB-EP010081MO
  • EUR 606.00
  • EUR 318.00
  • EUR 2192.40
  • EUR 919.20
  • EUR 1461.60
  • EUR 402.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Mouse Granzyme A(Gzma) expressed in E.coli

Mouse Granzyme A (Gzma)

1-CSB-EP010081MOa0
  • EUR 606.00
  • EUR 318.00
  • EUR 2192.40
  • EUR 919.20
  • EUR 1461.60
  • EUR 402.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Mouse Granzyme A(Gzma) expressed in E.coli

GZMA Polyclonal Conjugated Antibody

C42195 100ul
EUR 476.4

Mouse GZMA shRNA Plasmid

20-abx970717
  • EUR 961.20
  • EUR 1345.20
  • 150 µg
  • 300 µg

Gzma Antibody, HRP conjugated

1-CSB-PA010081LB01MO
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against Gzma. Recognizes Gzma from Mouse. This antibody is HRP conjugated. Tested in the following application: ELISA

Gzma Antibody, FITC conjugated

1-CSB-PA010081LC01MO
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against Gzma. Recognizes Gzma from Mouse. This antibody is FITC conjugated. Tested in the following application: ELISA

Gzma Antibody, Biotin conjugated

1-CSB-PA010081LD01MO
  • EUR 380.40
  • EUR 402.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against Gzma. Recognizes Gzma from Mouse. This antibody is Biotin conjugated. Tested in the following application: ELISA

Eukaryotic Granzyme A (GZMA)

4-EPA599Hu51
  • EUR 636.10
  • EUR 294.00
  • EUR 2055.36
  • EUR 765.12
  • EUR 1410.24
  • EUR 501.60
  • EUR 4958.40
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Granzyme A expressed in: Yeast

Recombinant Granzyme A (GZMA)

4-RPA599Mu01
  • EUR 657.60
  • EUR 300.00
  • EUR 2136.00
  • EUR 792.00
  • EUR 1464.00
  • EUR 516.00
  • EUR 5160.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Mouse Granzyme A expressed in: E.coli

GZMA Recombinant Protein (Rat)

RP204086 100 ug Ask for price

GZMA Recombinant Protein (Mouse)

RP140609 100 ug Ask for price

Granzyme A Antibody / GZMA

RQ5733 100 ug
EUR 419

Human Granzyme A (GZMA) ELISA Kit

20-abx151729
  • EUR 7970.40
  • EUR 4250.40
  • EUR 990.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Human Granzyme A (GZMA) ELISA Kit

abx253929-96tests 96 tests
EUR 904.8

Human Granzyme A (GZMA) ELISA Kit

20-abx585052
  • EUR 8853.60
  • EUR 4719.60
  • EUR 1093.20
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Human Granzyme A (GZMA) CLIA Kit

20-abx496426
  • EUR 9567.60
  • EUR 5095.20
  • EUR 1177.20
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Human Granzyme A (GZMA) CLIA Kit

20-abx491735
  • EUR 9567.60
  • EUR 5095.20
  • EUR 1177.20
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Human Granzyme A (GZMA) ELISA Kit

abx571746-96tests 96 tests
EUR 904.8

Human Granzyme A (GZMA) Protein (Active)

20-abx655652
  • EUR 1429.20
  • EUR 510.00
  • EUR 4820.40
  • EUR 1746.00
  • EUR 978.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Human granzyme A (GZMA) ELISA Kit

CSB-E08715h-24T 1 plate of 24 wells
EUR 198
Description: Quantitativesandwich ELISA kit for measuring Human granzyme A (GZMA) in samples from serum, plasma, cell culture supernates, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Human granzyme A (GZMA) ELISA Kit

1-CSB-E08715h
  • EUR 1080.00
  • EUR 6571.20
  • EUR 3480.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Human granzyme A (GZMA) in samples from serum, plasma, cell culture supernates, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Human GZMA(Granzyme A) ELISA Kit

EH0974 96T
EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 9.375pg/ml

Human GZMA/ Granzyme A ELISA Kit

E1079Hu 1 Kit
EUR 685.2

Human Granzyme A, GZMA ELISA KIT

ELI-02157h 96 Tests
EUR 988.8

Human Granzyme A (GZMA) ELISA Kit

SEA599Hu-10x96wellstestplate 10x96-wells test plate
EUR 5128.02
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Granzyme A (GZMA) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Human Granzyme A (GZMA) ELISA Kit

SEA599Hu-1x48wellstestplate 1x48-wells test plate
EUR 527.48
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Granzyme A (GZMA) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Human Granzyme A (GZMA) ELISA Kit

SEA599Hu-1x96wellstestplate 1x96-wells test plate
EUR 702.12
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Granzyme A (GZMA) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Human Granzyme A (GZMA) ELISA Kit

SEA599Hu-5x96wellstestplate 5x96-wells test plate
EUR 2799.54
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Granzyme A (GZMA) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Human Granzyme A (GZMA) ELISA Kit

4-SEA599Hu
  • EUR 5188.80
  • EUR 2739.60
  • EUR 703.20
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Granzyme A (GZMA) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids with no significant corss-reactivity with analogues from other species.

Human Granzyme A ELISA Kit (GZMA)

RK01528 96 Tests
EUR 625.2

Platinum-E Retroviral Packaging Cell Line, Ecotropic

RV-101 1 vial
EUR 1104
Description: Conventional cells used for retrovirus packaging, such as those based on NIH3T3 cells, have limited stability and produce relatively low yields of retrovirus, mainly due to the poor expression of retroviral structure proteins (gag, pol and env) in the cells. The Platinum Retroviral Packaging Cell Lines are based on the 293T cell line. They exhibit longer stability and produce higher yields of retroviral structure proteins. Plat-E cells contain gag, pol and env genes, allowing retroviral packaging with a single plasmid transfection.

Platinum-A Retroviral Packaging Cell Line, Amphotropic

RV-102 1 vial
EUR 1104
Description: Conventional cells used for retrovirus packaging, such as those based on NIH3T3 cells, have limited stability and produce relatively low yields of retrovirus, mainly due to the poor expression of retroviral structure proteins (gag, pol and env) in the cells. The Platinum Retroviral Packaging Cell Lines are based on the 293T cell line. They exhibit longer stability and produce higher yields of retroviral structure proteins. Plat-A cells contain gag, pol and env genes, allowing retroviral packaging with a single plasmid transfection.

Platinum-GP Retroviral Packaging Cell Line, Pantropic

RV-103 1 vial
EUR 1104
Description: Conventional cells used for retrovirus packaging, such as those based on NIH3T3 cells, have limited stability and produce relatively low yields of retrovirus, mainly due to the poor expression of retroviral structure proteins (gag, pol and env) in the cells. The Platinum Retroviral Packaging Cell Lines are based on the 293T cell line. They exhibit longer stability and produce higher yields of retroviral structure proteins. Plat-GP cells contain the gag and pol genes required for retroviral packaging; an expression vector is co-transfected with a VSVG envelope vector.

Gzma sgRNA CRISPR Lentivector (Rat) (Target 1)

K7364802 1.0 ug DNA
EUR 184.8

Gzma sgRNA CRISPR Lentivector (Rat) (Target 2)

K7364803 1.0 ug DNA
EUR 184.8

Gzma sgRNA CRISPR Lentivector (Rat) (Target 3)

K7364804 1.0 ug DNA
EUR 184.8

Gzma sgRNA CRISPR Lentivector (Mouse) (Target 1)

K3890502 1.0 ug DNA
EUR 184.8

Gzma sgRNA CRISPR Lentivector (Mouse) (Target 2)

K3890503 1.0 ug DNA
EUR 184.8

Gzma sgRNA CRISPR Lentivector (Mouse) (Target 3)

K3890504 1.0 ug DNA
EUR 184.8

Total Protein - Murine Embryonic Stem Cell Line D3

CBA-305 500 ?g
EUR 414
Description:
  • Isolated from mouse ES-D3 cell line
  • Presented as 500 µg at 1 mg/mL in NP-40 Solubilization Buffer

GZMA sgRNA CRISPR/Cas9 All-in-One Lentivector set (Human)

K0923805 3 x 1.0 ug
EUR 451.2

Pipette Blow Out Milk 0.5-1ml

DAI2804 EACH
EUR 6.27

Hettich 4 Place Swing Out Rotor

GBA5699 EACH
EUR 1984.74

Swing out rotor 4 x microplates

CEN0148 EACH
EUR 1075.02

Hettich Swing Out Rotor 2 Place

CEN0353 EACH
EUR 899.46

Hettich Swing Out Rotor 4 Place

CEN0407 EACH
EUR 727.32

Rotor Swing out 4x100mL ID Seal

CEN2680 EACH
EUR 752.4

Hettich Swing Out Rotor 4 Place

CEN5014 EACH
EUR 1519.62

Hettich Swing Out Rotor 2 Place

CEN5020 EACH
EUR 1143.42

Hettich Swing Out Rotor 4 Place

CEN5034 EACH
EUR 1493.4

Microtube 0.5mL Conical w/out Cap

TUB1084 PK3000
EUR 96.9

Microtube 1.5mL Conical w/out Cap

TUB1088 PK3000
EUR 118.56

Microtube 2mL Conical w/out Cap

TUB1092 PK3000
EUR 118.56

ELISA kit for Human GZMA (Granzyme A)

ELK4608 1 plate of 96 wells
EUR 518.4
Description: A sandwich ELISA kit for detection of Granzyme A from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

GZMA ELISA Kit (Human) : 96 Wells (OKEH02762)

OKEH02762 96 Wells
EUR 794.4
Description: Description of target: Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here is a T cell- and natural killer cell-specific serine protease that may function as a common component necessary for lysis of target cells by cytotoxic T lymphocytes and natural killer cells. ;Species reactivity: Human;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.1 ng/mL

ELISA kit for Human GzmA (Granzyme A)

E-EL-H1616 1 plate of 96 wells
EUR 640.8
Description: A sandwich ELISA kit for quantitative measurement of Human GzmA (Granzyme A) in samples from Serum, Plasma, Cell supernatant

Granzyme A (GZMA) Polyclonal Antibody (Human, Mouse)

4-PAA599Mu01
  • EUR 283.20
  • EUR 2805.60
  • EUR 703.20
  • EUR 352.80
  • EUR 250.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human, Mouse Granzyme A (GZMA)

GZMA Protein Vector (Human) (pPB-C-His)

PV019069 500 ng
EUR 394.8

GZMA Protein Vector (Human) (pPB-N-His)

PV019070 500 ng
EUR 394.8

GZMA Protein Vector (Human) (pPM-C-HA)

PV019071 500 ng
EUR 394.8

GZMA Protein Vector (Human) (pPM-C-His)

PV019072 500 ng
EUR 394.8

Mouse Granzyme A (GZMA) Protein

20-abx167506
  • EUR 910.80
  • EUR 360.00
  • EUR 2865.60
  • EUR 1095.60
  • EUR 644.40
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Granzyme A (GZMA) Antibody (Biotin)

20-abx270997
  • EUR 510.00
  • EUR 276.00
  • EUR 1462.80
  • EUR 710.40
  • EUR 393.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Granzyme A (GZMA) Antibody Pair

20-abx370633
  • EUR 1914.00
  • EUR 1228.80
  • 10 × 96 tests
  • 5 × 96 tests

Granzyme A (Gzma) Antibody (HRP)

20-abx319043
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Granzyme A (Gzma) Antibody (FITC)

20-abx319044
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Granzyme A (Gzma) Antibody (Biotin)

20-abx319045
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Granzyme A (GZMA) Antibody (APC)

20-abx176700
  • EUR 1312.80
  • EUR 644.40
  • 1 mg
  • 200 ug

Polyclonal GZMA Antibody (internal region)

APG00588G 0.1mg
EUR 580.8
Description: A polyclonal antibody raised in Goat that recognizes and binds to Human GZMA (internal region). This antibody is tested and proven to work in the following applications:

GZMA ELISA Kit (Bovine) (OKEH06598)

OKEH06598 96 Wells
EUR 934.8
Description: Description of target: Abundant protease in the cytosolic granules of cytotoxic T-cells and NK-cells which activates caspase-independent cell death with morphological features of apoptosis when delivered into the target cell through the immunological synapse. It cleaves after Lys or Arg. Cleaves APEX1 after 'Lys-31' and destroys its oxidative repair activity. Cleaves the nucleosome assembly protein SET after 'Lys-189', which disrupts its nucleosome assembly activity and allows the SET complex to translocate into the nucleus to nick and degrade the DNA.;Species reactivity: Bovine;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.05 ng/mL

Gzma ORF Vector (Rat) (pORF)

ORF068030 1.0 ug DNA
EUR 607.2

GZMA ELISA Kit (Rat) (OKEI00778)

OKEI00778 96 Wells
EUR 920.4
Description: Description of target: ;Species reactivity: Rat;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.938 ng/mL

GZMA ELISA Kit (Mouse) (OKCD02583)

OKCD02583 96 Wells
EUR 934.8
Description: Description of target: Abundant protease in the cytosolic granules of cytotoxic T-cells and NK-cells which activates caspase-independent cell death with morphological features of apoptosis when delivered into the target cell through the immunological synapse. It cleaves after Lys or Arg. Cleaves APEX1 after 'Lys-31' and destroys its oxidative repair activity. Cleaves the nucleosome assembly protein SET after 'Lys-189', which disrupts its nucleosome assembly activity and allows the SET complex to translocate into the nucleus to nick and degrade the DNA. ;Species reactivity: Mouse;Application: ;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 35 pg/mL

Gzma ORF Vector (Mouse) (pORF)

ORF046871 1.0 ug DNA
EUR 607.2

Anti-Granzyme A/GZMA Antibody

PA1588 100ug/vial
EUR 400.8

Gzma Polyclonal Antibody, Biotin Conjugated

A59335-050 50 ul
EUR 302.5

Gzma Polyclonal Antibody, Biotin Conjugated

A59335-100 100 ul
EUR 423.5

Gzma Polyclonal Antibody, FITC Conjugated

A59336-050 50 ul
EUR 302.5

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